A commonly prescribed antidepressant, paroxetine, could possibly help in restoring heart failure, reveals a new research. Paroxetine has shown to inhibit a specific enzyme.
Antidepressants in Dementia - Less Benefit, More Side Effects
Antidepressants may provide little benefit in dementia patients suffering from depression, a study suggests. They appear to increase adverse effects instead.
Antidepressants may provide little benefit in dementia patients suffering from depression, a study suggests. They appear to increase adverse effects instead.
The team of researchers mentioned that when the heart muscle was damaged by a heart attack, the body attempts to compensate for its lost pumping power by increasing adrenaline levels to boost heart rate, and leads to a series of maladaptive adjustments, and the heart grows larger and less efficient as its contractile force weakens.
The study showed that during a heart attack, portions of the heart muscle deprived of oxygen by the blockage to cardiac circulation die, and GRK2 (G protein-coupled Receptor Kinase-2) actually induces even more cells to die, leading to patches of scar tissue that are unable to contract, to the weakening and thinning of the heart tissue and dilation of the heart.
Paroxetine Approved By FDA for Hot Flashes
Low-dose paroxetine has been approved by the FDA for the treatment of hot flashes.
Low-dose paroxetine has been approved by the FDA for the treatment of hot flashes.
The research is published in the journal Science Translational Medicine.
Advertisements
Researchers Decode Why Antidepressant May Be Effective in Postpartum Depression
Prescribed for women with postpartum depression, the antidepressants restore connections between cells in brain regions that are negatively affected by chronic stress during pregnancy.
Prescribed for women with postpartum depression, the antidepressants restore connections between cells in brain regions that are negatively affected by chronic stress during pregnancy.
Early Exposure to Antidepressants may Affect Adult Anxiety and Serotonin Transmission
More than 15 percent of women in the United States suffer from anxiety disorders and depression during their pregnancies, and many are prescribed antidepressants.
More than 15 percent of women in the United States suffer from anxiety disorders and depression during their pregnancies, and many are prescribed antidepressants.
