About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Antibiotics Stimulate the Growth of Bacteria
Advertisement

Antibiotics Stimulate the Growth of Bacteria

Font : A-A+

Highlights:
  • Antibiotics drugs are found to stimulate bacterial reproduction.
  • Mutated E.coli bacteria when exposed to eight rounds of antibiotic for four days, reproduce much faster and were three times larger than encountering the drugs.
  • It is necessary to choose the right antibiotic on patients so that there is no adaptations in the clinic.

Antibiotics were found to stimulate bacterial reproduction, finds a new study from the University of Exeter.

The research team exposed E.coli bacteria to eight rounds of antibiotic for over four days and found that the bug was capable of causing severe stomach pain, diarrhea and kidney failure among humans and had increased antibiotic resistance.

Advertisement


They were surprised to find mutated E.coli to have reproduced much faster and formed a population which was three times larger than before encountering the antibiotic drugs because of the mutations.

When the research team took the antibiotic drugs away, they found that the evolutionary changes were done and the new-found abilities remained.

Professor Robert Beardmore, University of Exeter, said, "Our research suggests there could be added benefits for E.coli bacteria when they evolve resistance to clinical levels of antibiotics."
Advertisement

"It's often said that Darwinian evolution is slow, but nothing could be further from the truth, particularly when bacteria are exposed to antibiotics."

"Bacteria have a remarkable ability to rearrange their DNA and this can stop drugs working, sometimes in a matter of days."

"While rapid DNA change can be dangerous to a human cell, to a bacterium like E.coli it can have multiple benefits, provided they hit on the right changes."

Efficacy of Doxycycline Antibiotic in E.Coli
The research team tested the effect of doxycycline antibiotic in E.coli bacteria to understand the changes in the DNA brought by the antibiotics.

The E.coli that was evolved were frozen at -80℃ and the research team also used genetic sequencing to find out DNA Changes that were responsible for unusual evolution.

Clinically, E.coli producing more antibiotic pumps were found to exploit the antibiotics out of the cell. And the loss of DNA is another well-known change that is known to describe the dormant virus.

Dr. Carlos Reding, said, "Our best guess is that losing viral DNA stops the E.coli destroying itself, so we see more bacterial cells growing once the increase in pump DNA allows them to resist the antibiotic in the first place."

Dr Mark Hewlett, University of Exeter, added, "It is said by some that drug resistance evolution doesn't take place at high dosages but our paper shows that it can and that bacteria can change in ways that would not be beneficial for the treatment of certain types of infection."

"This shows it's important to use the right antibiotic on patients as soon as possible so we don't see adaptations like these in the clinic."

The current study uses liquid conditions, so that the E.coli bacteria can increase cell production.

References
  1. Carlos Reding-Roman et al, The unconstrained evolution of fast and efficient antibiotic-resistant bacterial genomes, Nature Ecology & Evolution (2017). DOI: 10.1038/s41559-016-0050

Citations   close

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Madhumathi Palaniappan. (2017, January 30). Antibiotics Stimulate the Growth of Bacteria. Medindia. Retrieved on May 16, 2022 from https://www.medindia.net/news/healthwatch/antibiotics-stimulate-the-growth-of-bacteria-167369-1.htm.

  • MLA

    Madhumathi Palaniappan. "Antibiotics Stimulate the Growth of Bacteria". Medindia. May 16, 2022. <https://www.medindia.net/news/healthwatch/antibiotics-stimulate-the-growth-of-bacteria-167369-1.htm>.

  • Chicago

    Madhumathi Palaniappan. "Antibiotics Stimulate the Growth of Bacteria". Medindia. https://www.medindia.net/news/healthwatch/antibiotics-stimulate-the-growth-of-bacteria-167369-1.htm. (accessed May 16, 2022).

  • Harvard

    Madhumathi Palaniappan. 2021. Antibiotics Stimulate the Growth of Bacteria. Medindia, viewed May 16, 2022, https://www.medindia.net/news/healthwatch/antibiotics-stimulate-the-growth-of-bacteria-167369-1.htm.

Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World Hypertension Day 2022 - Measure Blood Pressure Accurately, Control It, Live Longer!
Drinking This Popular Beverage May Drop Dementia Risk
Worst Mistakes Parents Make When Talking to Kids
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Shigellosis MRSA - The Super Bug Food Safety for Health Antibiotics Eye Infections Natural Antibiotics to Fight Bacterial Infections Vancomycin-Resistant Enterococci (VRE) Boils - Treatment by Drugs Multiple Drug Allergy Syndrome Interaction of Antibiotics with Dairy Products 

Most Popular on Medindia

The Essence of Yoga Hearing Loss Calculator Drug Side Effects Calculator Iron Intake Calculator Nutam (400mg) (Piracetam) A-Z Drug Brands in India Accident and Trauma Care Color Blindness Calculator Blood - Sugar Chart Blood Donation - Recipients

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use