Arthritis is a chronic inflammatory condition with no known etiology. While the synovial membranes of joints are mainly prone to damage, it can also lead to extra-articular tissues in the eye, skin, lungs, heart and peripheral nerves. Arthritis has been closely correlated with the incidence of eye conditions like inflammation of the uvea (uveitis) and inflammation of the sclera of the eye (scleritis).
The famous Italian astronomer, physicist and philosopher Galileo Galilei presented
several correlated disorders in his lifetime of which chronic arthritic pain and bilateral blindness were most significant.
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Reiters Syndrome
Reiters syndrome, Reactive arthritis or Reiters disease is an autoimmune condition that has several names.
Reiters syndrome, Reactive arthritis or Reiters disease is an autoimmune condition that has several names.
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‘The famous Italian astronomer, physicist and philosopher Galileo Galilei suffered from recurrent bouts of arthritis which eventually turned to uveitis and bilateral blindness.’
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Italian researchers Zanatta, Zampieri, Bonati, Liessi, Barbieri et al, conducted a series of anthropological and radiographic analyzes on the fifth lumbar vertebra of Galileo owned by Padua University. The objective was to achieve a new diagnostic hypothesis of correlation between reactive arthritis and uveitis.
The researchers used multimodal materials and methods to advance their hypothesis. Using Galileo's letters and other personal and historical documents, they hypothesized that he must have been suffering from reactive arthritis. A study of his fifth lumbar vertebra provided information on the
pathologies he suffered in his lifetime. Researchers used osteological measurements to confirm their hypothesis.
![Rheumatoid Arthritis]( "Rheumatoid Arthritis")
Measurements indicated that the vertebra was normal without any significant disease from an anthropological point of view. Digital radiography and computed tomography indicated mild arthrosis correlated with a small osteophytosis (outgrowths of bone tissue). In Galileo's case, the immune rheumatic disease or reactive arthritis led to bilateral blindness due to a pannus (abnormal layer of fibrovascular tissue) restricting the pupils (uveitis).
The above findings indicate that Galileo was suffering from reactive arthritis Galileo used to suffer from recurrent bouts of arthritis which eventually turned to uveitis and bilateral blindness.
During his lifetime, Galileo led a merry life. He was a big eater, drinker and sexually active. When he was 29 years of age, he suffered from a severe illness which he held responsible for his subsequent ill-health. In the early summer of 1593, Galileo and his friends spent a weekend in a villa of Costozza near Vicenza of Count Camillo Trento. After a meal and wine with friends, he slept in a room known as "Sala dei Venti" or wind room. This room was constantly cooled by air circulating through large ventiducts from the nearby caves. Galileo and his friends woke up with high fever, cramps, chills, hemorrhages, headache and fatigue. Two of them died. Galileo survived but remained deaf for almost a year.
It was from this incident onwards that Galileo suffered from arthritic pains. His arthritic pains were confirmed by his son Vincenzio Galilei who reported to Galileo's biographer Vincenzo Viviani that his father suffered from recurrent arthritic pains which varied in intensity depending on the season. Viviani traces Galileo's arthritic pains to the incident in the wind room.
When it comes to Galileo's blindness, he was diagnosed by a Roman surgeon Giovanni Trulio via a letter document. With the help of this document, the researchers were able to hypothesize uveitis and correlate it with his rheumatic disorder. The blindness was evident from Galileo's signature which became uncertain and shaky.
The hypothesis of blindness due to uveitis is most plausible as it also explains the arthritic pains suffered by Galileo. This reactive arthritis is usually correlated to three inflammatory conditions: conjunctivitis, urethritis and arthritis. The researchers also hypothesize that Galileo might have suffered urethritis due to venereal disease.
According to the researchers, this reactive arthritis could have been triggered by a Chlamydia pneumonia infection during the illness episode in the wind room. This evolved into chronic arthritis as it is evident by the frequent and long episodes of joint pain which Galileo often complained. Recurrent arthritis ultimately led to uveitis and bilateral blindness.
References : 1. Thiene, G. & Basso, C. (2011). Galileo as a Patient. The Inspiration of Astronomical Phenomena VI ASP Conference Series, Vol. 441 Enrico Maria Corsini, ed. Retrieved on 30 October 2015 from http://adsabs.harvard.edu/full/2011ASPC..441...73T
2. Rheumatoid Arthritis Associated Scleritis. Fehma Tufail M.D. Retrieved on 30 October 2015 from
http://www.uveitis.org/docs/dm/rheumatoid_arthritis_associated_scleritis.pdf
3. Scleral Inflammations: An Update. (2013). Published by All India Ophthalmological Society.
4. Zanatta, A., Zampieri, F., Bonati, R.M., Liessi, G., Barbieri. C et al. (2015). New Interpretation of Galileo's Arthritis and Blindness. Advances in Anthropology, 5, 39-49. Published Online February 2015 in SciRes.
http://www.scirp.org/journal/aa
http://dx.doi.org/10.4236/aa.2015.51005
4. http://www.bbc.co.uk/history/historic_figures/galilei_galileo.shtml
Source: Medindia
Rheumatoid Arthritis
Rheumatoid arthritis is a chronic inflammatory disease that causes pain, swelling, stiffness and loss of function in the joints.
Rheumatoid arthritis is a chronic inflammatory disease that causes pain, swelling, stiffness and loss of function in the joints.
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Measurements indicated that the vertebra was normal without any significant disease from an anthropological point of view. Digital radiography and computed tomography indicated mild arthrosis correlated with a small osteophytosis (outgrowths of bone tissue). In Galileo's case, the immune rheumatic disease or reactive arthritis led to bilateral blindness due to a pannus (abnormal layer of fibrovascular tissue) restricting the pupils (uveitis).
The above findings indicate that Galileo was suffering from reactive arthritis Galileo used to suffer from recurrent bouts of arthritis which eventually turned to uveitis and bilateral blindness.
During his lifetime, Galileo led a merry life. He was a big eater, drinker and sexually active. When he was 29 years of age, he suffered from a severe illness which he held responsible for his subsequent ill-health. In the early summer of 1593, Galileo and his friends spent a weekend in a villa of Costozza near Vicenza of Count Camillo Trento. After a meal and wine with friends, he slept in a room known as "Sala dei Venti" or wind room. This room was constantly cooled by air circulating through large ventiducts from the nearby caves. Galileo and his friends woke up with high fever, cramps, chills, hemorrhages, headache and fatigue. Two of them died. Galileo survived but remained deaf for almost a year.
It was from this incident onwards that Galileo suffered from arthritic pains. His arthritic pains were confirmed by his son Vincenzio Galilei who reported to Galileo's biographer Vincenzo Viviani that his father suffered from recurrent arthritic pains which varied in intensity depending on the season. Viviani traces Galileo's arthritic pains to the incident in the wind room.
When it comes to Galileo's blindness, he was diagnosed by a Roman surgeon Giovanni Trulio via a letter document. With the help of this document, the researchers were able to hypothesize uveitis and correlate it with his rheumatic disorder. The blindness was evident from Galileo's signature which became uncertain and shaky.
The hypothesis of blindness due to uveitis is most plausible as it also explains the arthritic pains suffered by Galileo. This reactive arthritis is usually correlated to three inflammatory conditions: conjunctivitis, urethritis and arthritis. The researchers also hypothesize that Galileo might have suffered urethritis due to venereal disease.
According to the researchers, this reactive arthritis could have been triggered by a Chlamydia pneumonia infection during the illness episode in the wind room. This evolved into chronic arthritis as it is evident by the frequent and long episodes of joint pain which Galileo often complained. Recurrent arthritis ultimately led to uveitis and bilateral blindness.
References : 1. Thiene, G. & Basso, C. (2011). Galileo as a Patient. The Inspiration of Astronomical Phenomena VI ASP Conference Series, Vol. 441 Enrico Maria Corsini, ed. Retrieved on 30 October 2015 from http://adsabs.harvard.edu/full/2011ASPC..441...73T
2. Rheumatoid Arthritis Associated Scleritis. Fehma Tufail M.D. Retrieved on 30 October 2015 from
http://www.uveitis.org/docs/dm/rheumatoid_arthritis_associated_scleritis.pdf
3. Scleral Inflammations: An Update. (2013). Published by All India Ophthalmological Society.
4. Zanatta, A., Zampieri, F., Bonati, R.M., Liessi, G., Barbieri. C et al. (2015). New Interpretation of Galileo's Arthritis and Blindness. Advances in Anthropology, 5, 39-49. Published Online February 2015 in SciRes.
http://www.scirp.org/journal/aa
http://dx.doi.org/10.4236/aa.2015.51005
4. http://www.bbc.co.uk/history/historic_figures/galilei_galileo.shtml
Source: Medindia
Top Ten Facts On Blindness
Visual handicap has been a blind spot for governments globally for very long. Especially in India, blindness prevalence has increased dramatically, mostly due to avoidable causes for which simplified treatments are also available these days. Here are the top ten facts on blindness in India and around the world.
Visual handicap has been a blind spot for governments globally for very long. Especially in India, blindness prevalence has increased dramatically, mostly due to avoidable causes for which simplified treatments are also available these days. Here are the top ten facts on blindness in India and around the world.
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 Quiz on Arthritis Do you know that there are more than 100 types of arthritis? If you think that only old people suffer from arthritis, take this intriguing quiz to get your facts on arthritis. | Advertisement
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