Highlights:
- Prostate cancer is the second leading cause of cancer death for men in the U.S., that is primarily determined using PSA (Prostate-Specific Antigen) test
- The diagnostic accuracy of the PSA is as low as 30%, requiring additional invasive biopsies
- A new electrical-signal-based ultrasensitive biosensor can diagnose prostate cancer from the urine within twenty minutes with almost 100% accuracy
- The utilization of a smart Artificial Intelligence (AI) method allows to analyze the complex patterns of cancer factors in urine samples and derive the diagnosis
Prostate cancer is the second leading cause of cancer death for men in the U.S. It is primarily determined using PSA (Prostate-Specific Antigen) test, a cancer factor in the blood. But the diagnostic accuracy is as low as 30%, and additional invasive biopsies are required to confirm the diagnosis causing bleeding and pain in patients.
Prostate cancer can now be diagnosed from the urine within twenty minutes with almost 100% accuracy, using a smart Artificial Intelligence (AI) analysis method and an electrical-signal-based ultrasensitive biosensor, as per the research team at The Korea Institute of Science and Technology (KIST).
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Prostate Cancer: Treatment Options
Treatment options of prostate cancer includes waiting, surgery, radiation, hormone therapy, chemotherapy, cryosurgery or biologic therapy.
Treatment options of prostate cancer includes waiting, surgery, radiation, hormone therapy, chemotherapy, cryosurgery or biologic therapy.
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‘A new electrical-signal-based ultrasensitive biosensor can diagnose prostate cancer from the urine within twenty minutes with almost 100% accuracy. Utilizing a smart Artificial Intelligence (AI) method allows analyzing the intricate patterns of cancer factors in urine samples and deriving the diagnosis.’
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This non-invasive diagnostic method makes it convenient for prostate cancer patients as it utilizes urine thus, minimizing the need for invasive biopsy and side effects. But as the concentration of cancer factors (a cancer-related biological index) remains low in urine, the urine-based biosensor is so far used to classify the risk groups than accurately diagnosing the patients.
Artificial Intelligence in Prostate Cancer Diagnosis
The research team deployed different types of cancer factors using the electrical-signal-based ultrasensitive biosensor rather than employing only one factor to enhance the diagnostic accuracy innovatively to over 90%.
This ultrasensitive semiconductor sensor system can simultaneously measure trace amounts of four selected cancer factors in the urine and provide a diagnosis for prostate cancer.
![Quiz on Prostate Cancer]( "Quiz on Prostate Cancer")
"For patients who need surgery and/or treatments, cancer will be diagnosed with high accuracy by utilizing urine to minimize unnecessary biopsy and treatments, which can dramatically reduce medical costs and medical staff's fatigue," says Professor Jeong at Asan Medical Center
The team trained an AI algorithm for identifying the correlation between the four cancer factors and analyzing their complex patterns of the detected signals to provide the diagnosis from the developed sensor. The AI analysis was able to detect 76 urinary samples successfully with almost 100 percent accuracy.
"This research developed a smart biosensor that can rapidly diagnose prostate cancer with almost 100 percent accuracy only through a urine test, and it can be further utilized in the precise diagnoses of other cancers using a urine test," says Dr. Lee at the KIST.
Reference :
Source: Medindia
Quiz on Prostate Cancer
Prostate cancer is fast gaining as a common cancer form among men; more threatening since its symptoms often go unnoticed until it's too late. This quiz tests your knowledge on prostate cancer, its diagnosis and treatment options and is as mandatory for men as the screening tests mentioned here are!
Prostate cancer is fast gaining as a common cancer form among men; more threatening since its symptoms often go unnoticed until it's too late. This quiz tests your knowledge on prostate cancer, its diagnosis and treatment options and is as mandatory for men as the screening tests mentioned here are!
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"For patients who need surgery and/or treatments, cancer will be diagnosed with high accuracy by utilizing urine to minimize unnecessary biopsy and treatments, which can dramatically reduce medical costs and medical staff's fatigue," says Professor Jeong at Asan Medical Center
The team trained an AI algorithm for identifying the correlation between the four cancer factors and analyzing their complex patterns of the detected signals to provide the diagnosis from the developed sensor. The AI analysis was able to detect 76 urinary samples successfully with almost 100 percent accuracy.
"This research developed a smart biosensor that can rapidly diagnose prostate cancer with almost 100 percent accuracy only through a urine test, and it can be further utilized in the precise diagnoses of other cancers using a urine test," says Dr. Lee at the KIST.
Top AI Applications in Healthcare
The top applications of artificial intelligence that could change healthcare include:- Robot-assisted surgery
- Virtual nursing assistants Fraud detection
- Dosage error reduction
- Clinical trial participation
- Cybersecurity
Reference :
- Hojun Kim et al, Noninvasive Precision Screening of Prostate Cancer by Urinary Multimarker Sensor and Artificial Intelligence Analysis, ACS Nano (2020). DOI:10.1021/acsnano.0c06946
Source: Medindia
Quiz on Cancer
Cancer, is the second most leading cause of death worldwide. Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Take this quiz on and test how much you know about cancer.
Cancer, is the second most leading cause of death worldwide. Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Take this quiz on and test how much you know about cancer.
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 Biological Clock May Offer Treatment for Prostate Cancer One of the regulators of our biological or circadian clock - CRY-1 is found to be involved in prostate cancer progression by altering the cancer cell's DNA repair mechanism. | Advertisement
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![Prostate Specific Antigen [PSA]](https://www.medindia.net/images/patientinfo/120x100/prostate-specific-antigen.jpg "Prostate Specific Antigen [PSA]")
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