New study finds that a diet with compounds found in green tea and carrots reversed Alzheimer's-like symptoms in mice. This study could one day pave the way for treatment of dementia in humans. The findings of the study are published in the journal Biological Chemistry.
The study, led by the University of Southern California in the US, supports the idea that combination therapy, rather than a single magic bullet, may offer the best approach to treating people living with Alzheimer's.
Diseases Related to Old Age
Ageing is referred to the accumulation of changes that brings a person closer to death.
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‘A combination of epigallocatechin-3-gallate found in green tea and ferulic acid found in carrots, tomatoes, wheat, rice, and oats restored spatial working memory completely.
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Combination treatment is already the standard of care for diseases such as cancer, HIV infection and rheumatoid arthritis.
After three months of treatment, the Alzheimer's mice performed just as well as the healthy comparison mice.
"You don't have to wait 10 to 12 years for a designer drug to make it to the market. You can make these dietary changes today. I find that very encouraging," said Terrence Town, Professor at the varsity.
![High Blood Pressure in Later Life May Link to Alzheimer]( "High Blood Pressure in Later Life May Link to Alzheimer")
High blood pressure (hypertension) in older people may increase signs of brain disease such as plaques and tangles linked to Alzheimer's disease, and brain lesions called infarcts.
For the study, the researchers assigned 32 mice with Alzheimer's-like symptoms to one of four groups with an equal number of males and females for three months.
The dosage was 30 milligrams per kilogram of body weight - a dosage well-tolerated by humans and easily consumed as part of a healthy diet.
The researchers noted that many mouse discoveries never translate into human treatments.
However, the findings lend credence to the idea that certain readily available, plant-based supplements might offer protection against dementia in humans, they said.
Source: IANS
"You don't have to wait 10 to 12 years for a designer drug to make it to the market. You can make these dietary changes today. I find that very encouraging," said Terrence Town, Professor at the varsity.
High Blood Pressure in Later Life May Link to Alzheimer's Disease
High blood pressure (hypertension) in older people may increase signs of brain disease such as plaques and tangles linked to Alzheimer's disease, and brain lesions called infarcts.
Advertisement
For the study, the researchers assigned 32 mice with Alzheimer's-like symptoms to one of four groups with an equal number of males and females for three months.
The dosage was 30 milligrams per kilogram of body weight - a dosage well-tolerated by humans and easily consumed as part of a healthy diet.
The researchers noted that many mouse discoveries never translate into human treatments.
However, the findings lend credence to the idea that certain readily available, plant-based supplements might offer protection against dementia in humans, they said.
Source: IANS
Liver Function and Diet may Affect Alzheimer's Disease Risk
Alzheimer's disease risk is impacted by the liver and diet, reports a research team at the University of Pennsylvania School of Medicine. This may happen when the liver fails to supply plasmalogens, key lipids to the brain.
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 'Game-Changing' Discovery for Patients With Alzheimer's DiseaseBy discovering the culprit behind decreased blood flow in the brain of people with Alzheimer's, researchers have made possible promising new therapies for the disease. | Advertisement
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