About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Genetically Modified Chickens Offer Hope for Cheaper Drugs

by Colleen Fleiss on January 29, 2019 at 5:01 AM
Font : A-A+

Genetically Modified Chickens Offer Hope for Cheaper Drugs

Gene modified chickens which produce human proteins in their eggs were found to offer a cost-effective method of producing certain types of drugs, a new research suggests.

The study -- which has initially focused on producing high quality proteins for use in scientific research -- found the drugs working just as well as the same proteins produced using existing methods.

Advertisement


High quantities of the proteins can be recovered from each egg using a simple purification system and there are no adverse effects on the chickens themselves, which lay eggs as normal, suggests the study published in the journal BMC Biotechnology.

"We are not yet producing medicines for people, but this study shows that chickens are commercially viable for producing proteins suitable for drug discovery studies and other applications in biotechnology," said co-author Helen Sang, Professor at the University of Edinburgh.
Advertisement

Eggs are already used for growing viruses that are used as vaccines, such as the flu jab.

This new approach is different because the therapeutic proteins are encoded in the chicken's DNA and produced as part of the egg white. For the study, the team initially focused on two proteins that are essential to the immune system and have therapeutic potential -- a human protein called IFNalpha2a, which has powerful antiviral and anti-cancer effects, and the human and pig versions of a protein called macrophage-CSF, which is being developed as a therapy that stimulates damaged tissues to repair themselves.

Just three eggs were enough to produce a clinically relevant dose of the drug. As chickens can lay up to 300 eggs per year, researchers say their approach could be more cost-effective than other production methods for some important drugs.

"We are excited to develop this technology to its full potential, not just for human therapeutics in the future but also in the fields of research and animal health," said co-author Lissa Herron from the varsity.

The team noted that the findings provide sound evidence for using chickens as a cheap method of producing high quality drugs for use in research studies and, potentially one day, in patients.

Source: IANS
Advertisement
Advertisement
Advertisement

Recommended Reading

This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Genetically Modified Chickens Offer Hope for Cheaper Drugs Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests