Fingerprint linked to a person's sleep habits and fluctuations in miRNA levels were found to serve as a warning or guide to disease stage and progression, revealed study findings.
New research in Experimental Physiology may have figured out why lack of sleep increases susceptibility to heart disease, and allowing doctors to identify the patients who might need to change their habits before they develop disease.
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‘Chronic short sleep is associated with increased risk of clogged arteries, heart disease, and thus increased morbidity and mortality. ’
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In adults who regularly slept fewer than 7 hours per night, the levels of certain microRNAs, (molecules that influence whether or not a gene is expressed) were lower. These molecules play a key role in regulating vascular health and thus levels are now recognized to be sensitive and specific biomarkers of cardiovascular health, inflammation and disease. In other words, a lowered level of these molecules is associated with heart disease, so they could be used as a biomarker to determine who is more susceptible to disease.
Researchers tested sedentary, middle-aged adults without heart disease from the local major metropolitan surrounding Denver and Boulder, Colorado. Subjects were asked to complete a questionnaire designed to accurately estimate average nightly sleep and a small amount of blood was taken from each subject after an overnight fast. MicroRNAs 125a, 126 and 146a were extracted from the blood and measured.
Jamie Hijmans, an author on the study said: "The link between insufficient sleep and cardiovascular disease may be due, in part, to changes in microRNAs.
Source: Eurekalert
Jamie Hijmans, an author on the study said: "The link between insufficient sleep and cardiovascular disease may be due, in part, to changes in microRNAs.
Source: Eurekalert
Quiz on Sleep Disorder
The comfort of modern life comes at the cost of restful sleep! "Laugh and the world laughs with you, snore and you sleep alone-Anthony Burgess" Scientifically it is proven that a good night's sleep is imperative for maintaining a balance between the physical, emotional and behavioral well-being of a person.
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Foods Inducing Sound Sleep
Insomnia has become a serious health problem and people tend to depend on quick yet risky solutions to get rid of it. But here is the list of nature's best sleep inducing foods right in our kitchen.
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