Aggressive fluid and sodium restriction has no effect on weight loss or clinical stability at three days but was associated with an increase in perceived thirst, suggests a clinical trial of 75 patients hospitalized with acute decompensated heart failure (ADHF).
This is according to a study published Online First by JAMA Internal Medicine, a JAMA Network publication.
Congestive Heart Failure
Congestive heart failure (CHF) is a condition in which the heart fails to work adequately as a pump that can deliver oxygen rich blood to the body.
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Sodium and fluid restrictions are nonpharmacologic measures widely used to treat ADHF despite a lack of clear evidence of their therapeutic effect, the authors write in the study background.
"We conclude that sodium and water restriction in patients admitted for ADHF are unnecessary," Graziella Badin Aliti, R.N., Sc.D., of the Hospital de Clìnicas de Porto Alegre, Brazil, and colleagues comment in the study.
![Helping Patients Cope With End-Stage Heart Failure]( "Helping Patients Cope With End-Stage Heart Failure")
Congestive heart failure is ultimately fatal, but the duration and quality of life leading up to death can be very unpredictable.
The clinical trial compared the effects of a fluid-restricted (maximum fluid intake, 800 mL/d) and sodium-restricted (maximum dietary intake, 800 mg/d) diet in an intervention group (IG) versus a diet with no such restrictions in a control group (CG). The main outcomes the authors measured were weight loss and clinical stability at the three-day assessment, as well as daily perception of thirst and readmissions within 30 days.
According to the results, weight loss was similar in both groups (between-group difference in variation of 0.25kg) as well as the change in clinical congestion score (between-group difference in variation of 0.59 points) at three days. Thirst was increased in the IG, but there were no significant between-group differences in the readmission rate at 30 days, the results indicate.
"In summary, this RCT contributes to the field of HF [heart failure] research by showing that, in patients with ADHF, aggressive fluid and sodium restriction had no effect on weight loss or clinical stability compared with a diet with liberal fluid and sodium intakes. Furthermore, this aggressive intervention was associated with significantly higher rates of perceived thirst," the study concludes.
(JAMA Intern Med. Published online May 20, 2013. doi:10.1001/jamainternmed.2013.552. Available pre-embargo to the media at http://media.jamanetwork.com.)
Source: Newswise
Helping Patients Cope With End-Stage Heart Failure
Congestive heart failure is ultimately fatal, but the duration and quality of life leading up to death can be very unpredictable.
Advertisement
The clinical trial compared the effects of a fluid-restricted (maximum fluid intake, 800 mL/d) and sodium-restricted (maximum dietary intake, 800 mg/d) diet in an intervention group (IG) versus a diet with no such restrictions in a control group (CG). The main outcomes the authors measured were weight loss and clinical stability at the three-day assessment, as well as daily perception of thirst and readmissions within 30 days.
According to the results, weight loss was similar in both groups (between-group difference in variation of 0.25kg) as well as the change in clinical congestion score (between-group difference in variation of 0.59 points) at three days. Thirst was increased in the IG, but there were no significant between-group differences in the readmission rate at 30 days, the results indicate.
"In summary, this RCT contributes to the field of HF [heart failure] research by showing that, in patients with ADHF, aggressive fluid and sodium restriction had no effect on weight loss or clinical stability compared with a diet with liberal fluid and sodium intakes. Furthermore, this aggressive intervention was associated with significantly higher rates of perceived thirst," the study concludes.
(JAMA Intern Med. Published online May 20, 2013. doi:10.1001/jamainternmed.2013.552. Available pre-embargo to the media at http://media.jamanetwork.com.)
Source: Newswise
Heart Failure Damage 'to be Reversed' by a Single Injection
Researchers have moved a step closer towards a single injection that could halt the damages of a devastating heart failure and even help repair and reverse the harm of heart failure.
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 Study Discussed Outcomes for Treating Heart Failure With Cell Therapy, High-dose UltrasoundAccording to a study, treatment that consisted of shock wave mediated preconditioning of the target heart tissue was associated with significant, albeit modest improvement. | Advertisement
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