About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Early Diagnosis of Testicular Cancer in Down Syndrome Patients

by Anjali Aryamvally on October 15, 2017 at 10:32 AM
Font : A-A+

Early Diagnosis of Testicular Cancer in Down Syndrome Patients

"Delay in Diagnosis of Testicular Cancer in a Patient with Down Syndrome" is a work published in the Journal of Cancer and Therapeutic Science, that focusses on the issue of testicular cancer in Down Syndrome patients. The study was headed by Jue Wang, MD, at the University of Arizona Cancer Center at Dignity Health St. Joseph's Hospital and Medical Center. Additionally "Detection and Treatment of Testicular Germ Cell Tumors in Men with Down Syndrome" will be presented in 2017 Mountain West Regional Society of General Internal Medicine (SGIM) annual conference.

The Phoenix-based research team was led by Dr. Wang, who is an internationally recognized testicular cancer specialist.

Advertisement


Testicular Cancer and Down Syndrome

Testicular cancers (TC) are rare in the general population, accounting for 1 percent of all human cancer. TC mainly affects young men between the ages of 15 to 35 years. Down syndrome (DS) is a genetic disorder caused by the presence of an extra copy of chromosome 21. Individuals with DS had an increased risk of testicular cancer. Although the curative rate for testicular cancer is high, delay in the diagnosis of testicular cancer is associated with greater morbidity and poorer prognosis. Due to their disability, patients with DS may not convey their symptoms effectively, often leading to delayed diagnosis and poor outcomes. Dr. Wang and his team reported their experience of successful treatment of a 29-year-old man with advanced stage testicular cancer which had spread to his lungs at the time of diagnosis.
Advertisement

The researchers established the largest cohort of TC in patients with DS. They found there is a higher rate of delayed or missed diagnosis of testicular cancer in patients with DS, in comparison with general population and that about 50 percent of patients were found in advanced stage. The researchers identified several factors contributed to the delayed diagnosis in this special population. "This research provides very important findings. It forms the basis of future guidelines for optimal management of these patients" said William G. Cance, MD, Deputy Director, University of Arizona Cancer Center at St. Joseph's Hospital and Medical Center.

"Since individuals with DS may not be able to effectively communicate their symptoms, this often leads to delayed diagnosis and potentially a worse outcome. We emphasize the need for improved communication skills with patients with learning disabilities, as well as conducting a thorough physical examination in these patients to avoid delayed diagnosis," says Dr. Wang who is the section chief of the Center's Genitourinary Oncology Division and also a professor of medicine at Creighton School of Medicine. Dr. Wang has served on several national oncology practice guideline committees such as The National Comprehensive Cancer Network. He also co-authored "Testicular Cancer Clinical Practice Guidelines in Oncology".

The goal for this research is to raise awareness of the increased incidence of testicular cancer in patients with DS and educate the community on the importance of early diagnosis and detection. Dr. Wang points out; "there is no advanced equipment that can replace a patient-physician relationship that is based on trust, compassion and effective communication."

Dr. Wang points out that the care of cancer patients with DS presents a challenge to doctors, nurses, families and caregivers at multiple levels. Based on their findings the research team is developing a multidisciplinary men's health/cancer program, and establishing a special algorithm and a tailored pathway to enhance patients and family experience. Going forward, the research will expand into the DS community in order to improve the current standard of care for cancer patients with learning or physical disability such as DS.



Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Black Tea Protects against Blood Pressure and Heart Diseases
Green Mediterranean Diet may Help Repair Age-Related Brain Damages
Cervical Cancer Awareness Month 2022
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Cancer and Homeopathy Cancer Facts Cancer Tattoos A Body Art Testicular Cancer Down Syndrome Testicular Self-Examination Common Lifestyle Habits that Cause Diseases Health Benefits of Dandelion Plant Disorders Included in Newborn Screening 

Recommended Reading
Testicular Cancer
A person with testicular cancer may have a testicle that is three times its original size. The most ...
Testicular Self-Examination
A testicular self-examination (TSE) helps in detecting cancer of the testicles. Doctors recommend .....
Gene Variations Increasing Testicular Cancer Risk Identified
Gene variations have been identified by a research team from the Institute of Cancer Research that ....
Men With Learning Disabilities More Likely to Develop Testicular Cancer
Men with learning difficulties have a 1 in 10 chance of dying from testicular cancer, compared to a ...
Common Lifestyle Habits that Cause Diseases
Cigarette smoking, unhealthy diets, overuse of alcohol, and physical inactivity are some of the most...
Disorders Included in Newborn Screening
Disorders included in newborn screening in US and India are discussed. Most disorders are either inh...
Down Syndrome
Down Syndrome is a congenital disorder among children commonly born to older mothers. The condition ...
Health Benefits of Dandelion Plant
What is dandelion? Dandelion greens are nutrition powerhouses with a wide range of health benefits. ...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT A DOCTOR
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)