About Careers MedBlog Contact us

Deeper or Longer Duration Cooling Did Not Reduce Risk of NICU Death

by Dr. Trupti Shirole on December 24, 2014 at 2:07 PM
Font : A-A+

 Deeper or Longer Duration Cooling Did Not Reduce Risk of NICU Death

Receiving deeper or longer duration cooling did not reduce risk of neonatal intensive care unit death when compared to usual care, among full-term newborns with moderate or severe hypoxic ischemic encephalopathy, according to scientists at the Wayne State University, Detroit.

Hypoxic ischemic encephalopathy i.e. damage to cells in the central nervous system from inadequate oxygen, is an important cause of childhood neuro-developmental deficits among infants born at full-term. Longer cooling and deeper cooling has been found to be neuro-protective in animal models. Hypothermia i.e. reduced body temperature at 33.5 degree C for 72 hours reduces death or disability.


364 full-term infants were randomly assigned to four hypothermia groups- 33.5 degree C for 72 hours, 32.0 degree C for 72 hours, 33.5 degree C for 120 hours, and 32.0 degree C for 120 hours, to examine if longer duration and deeper cooling would improve outcomes at 18 to 22 months.

The authors concluded, "Among neonates of at least 36 weeks' gestational age with moderate or severe hypoxic ischemic encephalopathy, deeper cooling or longer duration of cooling compared with hypothermia at 33.5 degree C for 72 hours did not reduce NICU death. These results have implications for patient care and the design of future trials."

The study is published in the 'JAMA'.

Source: Medindia


Latest Child Health News

Why Are Autism Rates Increasing in the U.S?
To tackle the rising cases of autism among kids, steady screening programs may make a difference in autism diagnosis and treatment.
Autistic Kids Often Miss Out on Vision Screening: Here's Why
Children with autism tend to receive vision screening less often, despite having a high risk for eye problems.
Why is Independent Play so Important for Kids?
Interrupting independent play time can affect the mental health of children. Engaging in independent activities can also reduce anxiety and depression in kids.
Children With Autism Show Link to Cardiometabolic Diseases
Obesity risk increases in children with autism spectrum disorder (ASD), raising the probability of developing cardiometabolic disorders.
125 Pediatric Flu Deaths Reported in the United States
125 pediatric influenza flu deaths have been reported so far this season in the United States, according to the CDC.
View All
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close

Deeper or Longer Duration Cooling Did Not Reduce Risk of NICU Death Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests