About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Chinese Medicinal Plant Helps Treat Cancer, Liver Disease

by Julia Samuel on April 11, 2016 at 2:13 PM
Font : A-A+

Chinese Medicinal Plant Helps Treat Cancer, Liver Disease

A plant used in traditional Chinese medicine produces compounds which may help treat cancer and liver diseases, find a team of scientists.

The research led by Professor Cathie Martin of the John Innes Centre revealed the secrets of a plant used as the traditional Chinese medicine. The Chinese skullcap, Scutellaria baicalensis, otherwise known in Chinese medicine as Huang-Qin, is traditionally used as a treatment for fever, liver and lung complaints.

Advertisement


Previous research on cells cultured in the lab has shown that certain compounds called flavones, found in the roots of this plant, not only have beneficial anti-viral and anti-oxidant effects, but they can also kill human cancers while leaving healthy cells untouched.

In live animal models, these flavones have also halted tumour growth, offering hope that they may one day lead to effective cancer treatments, or even cures.
Advertisement

As a group of compounds, the flavones are relatively well understood. But the beneficial flavones found in Huang-Qin roots, such as wogonin and baicalin, are different: a missing - OH (hydroxyl) group in their chemical structure left scientists scratching their heads as to how they were made in the plant.

Lead author Cathie Martin explained that many flavones are synthesised using a compound called naringenin as a building block. But naringenin has this -OH group attached to it, and there is no known enzyme that will remove it to produce the flavones we find in Huang-Qin roots. Working in collaboration with Chinese scientists, Cathie and her team explored the possibility that Huang-Qin's root-specific flavones (RSFs) were made via a different biochemical pathway.

Step-by-step, the scientists unravelled the mechanism involving new enzymes that make RSFs using a different building block called chrysin. "We believe that this biosynthetic pathway has evolved relatively recently in Scutellaria roots, diverging from the classical pathway that produces flavones in leaves and flowers, specifically to produce chrysin and its derived flavones," said Martin. The study is published in Science Advances. (ANI)

Source: ANI
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World Disability Day 2022 - The Role of Innovative Transformation
Diet and Oral Health: The Sugary Connection May Become Sour
World AIDS Day 2022 - Equalize!
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Alcoholic Liver Disease Liver Biopsy Hepatitis A Liver Wilson's Disease Biliary Cirrhosis Milk Thistle Current Treatments for Liver Cancer Fatty Liver Disease: A Growing Health Problem in India Living Donor Liver Transplant: What Are the Risks? 

Most Popular on Medindia

Loram (2 mg) (Lorazepam) Find a Doctor A-Z Drug Brands in India Blood - Sugar Chart Iron Intake Calculator Indian Medical Journals The Essence of Yoga Drug - Food Interactions Selfie Addiction Calculator Drug Interaction Checker
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close
×

Chinese Medicinal Plant Helps Treat Cancer, Liver Disease Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests