About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Camels Implicated in MERS Outbreak

by Dr. Enozia Vakil on April 30, 2014 at 9:13 PM
Font : A-A+

 Camels Implicated in MERS Outbreak

The camels in Saudi Arabia have been implicated in the ongoing outbreak of Middle East Respiratory Syndrome or MERS with more definitive evidences. Scientists at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health, King Saud University, and EcoHealth Alliance extracted a complete, live, infectious sample of MERS coronavirus from two camels in Saudi Arabia. The sample matched MERS coronavirus (MERS-CoV) found in humans, indicating that the virus in camels is capable of infecting humans and that camels are a likely source of the outbreak.

Results appear online in the journal mBio.

Advertisement

The researchers examined nasal samples collected during a countrywide survey of dromedary camels and selected samples from two animals with the highest viral load. They cultured and obtained complete genomic sequence from both animals as well as virus in nasal samples from several other camels.

The mathematical means of all genetic sequences (the consensus genomic sequences) were consistent with viruses found in human cases; however, samples from camels contained more than one virus genotype. Over a period of 48 hours of culture in primate cells, the genomic variation of viruses narrowed, mirroring the lower sequence diversity reported in MERS-CoV found in humans.
Advertisement

"The finding of infectious virus strengthens the argument that dromedary camels are reservoirs for MERS-CoV," says first author Thomas Briese, PhD, associate director of the Center for Infection and Immunity and associate professor of Epidemiology at the Mailman School. "The narrow range of MERS viruses in humans and a very broad range in camels may explain in part the why human disease is uncommon: because only a few genotypes are capable of cross species transmission," adds Dr. Briese.

"Given these new data, we are now investigating potential routes for human infection through exposure to camel milk or meat products," says co-author Abdulaziz N. Alagaili, PhD, director of the Mammals Research Chair at King Saud University. "This report builds on work published earlier this year when our team found that three-quarters of camels in Saudi Arabia carry MERS virus."

To date, at least 300 people have been infected with the virus that causes MERS and approximately 100 have died since the first documented case in Saudi Arabia in September 2012. Of these, more than 60—about one-fourth of the global total since MERS was identified—have been reported in the past month. Most cases have been in Saudi Arabia, with lower numbers in Jordan, Qatar, Tunisia, and the United Arab Emirates. France, Germany, Italy, and the United Kingdom, and more recently Malaysia and the Philippines, have also reported cases related to travel to the Middle East. While human-to-human transmission has occurred, the source of the disease in most cases has remained a mystery.

"Although there is no evidence that MERS-CoV is becoming more transmissible, the recent increase in reported cases is a cause for concern," says senior author W. Ian Lipkin, MD, director of the Center for Infection and Immunity and the John Snow Professor of Epidemiology at the Mailman School. "It is essential that investigators commit to data and sample sharing so that this potential threat to global health is addressed by the entire biomedical research community."
Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
First Dose of COVID-19 Vaccines May Improve Mental Health
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Middle East Respiratory Syndrome 

Recommended Reading
MERS Death Toll Hits 105, With 3 New Deaths Announced by Saudi
Three new deaths from the MERS coronavirus was announced Tuesday by Saudi health authorities, in a ....
Progress Reported in Search for MERS Treatment
After the death toll from the MERS virus topped 100 in Saudi Arabia, US scientists say they have ......
Two Saudi Nationals Die of MERS, Taking Toll to 94
The health ministry has said that two Saudi nationals have died from MERS, taking the death toll ......
Middle East Respiratory Syndrome
MERS, a newly discovered respiratory disease, was recently reported in the Arabian region. MERS is c...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use