About My Health Careers Internship MedBlogs Contact us
Medindia
LOGIN REGISTER
Advertisement

British Researchers Develop New Technique to Spot Resistant Tuberculosis Faster

by Bidita Debnath on May 14, 2015 at 12:26 AM
Font : A-A+

British Researchers Develop New Technique to Spot Resistant Tuberculosis Faster

A new technique is being developed by a team of British researchers that reduces the time from weeks to days in genetically sequencing the bacteria causing tuberculosis.

"This could help health service providers to better treat disease, control transmission of this infection and monitor outbreaks," said scientists from University College London.

Advertisement

"Using the conventional methods, patients with resistant TB would need to wait for up to six weeks for antibiotic resistance testing," said senior author professor Judith Breuer from University College London.

"Our technique and the associated software could reduce testing for antimicrobial resistance to a few days, allowing doctors to give precise antimicrobial treatment earlier than is currently possible," Breuer noted.
Advertisement

The whole genome sequencing reveals the complete genetic (DNA) sequence of an Mtb sample, in many cases pinpointing drug resistance mutations so that appropriate treatments can be given.

The new method allows scientists to enrich Mtb DNA directly from patient sputum (mucus) samples. The samples can be sequenced and analyzed straight away, avoiding the need to spend weeks growing them in the lab.

To extract Mtb from sputum samples, the researchers used probes made of ribonucleic acid (RNA) molecules, engineered to bind to Mtb DNA. The sequencing results from sputum matched perfectly with those from the relevant cultured isolates.

"As well as delivering personalized treatments to patients, the tests could also be used to precisely track the spread of TB," explained co-lead author Josephine Bryant from UCL Infection & Immunity).

The study was published in the Journal of Clinical Microbiology.

Source: IANS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Emotional Healing
Psychosis Risk Related to Cat Parasite
Sedentary Behavior Precipitates Night-Time Hot Flashes
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Tuberculosis Tracheostomy Pleural Effusion Silicosis Screening Tests for Tuberculosis Fever Cough Symptom Evaluation Diet in Tuberculosis Stomach Tuberculosis Extra Pulmonary Tuberculosis 

Recommended Reading
New Tuberculosis Drug, Bedaquiline, Offers Glimmer of Hope in South Africa
Tuberculosis, a contagious bacterial infection of the lungs, is one of the world's most deadly ......
In the Future, A Simple Blood Test may Accurately Diagnose Tuberculosis
Researchers have identified blood-based bio-markers in patients with active TB. This could lead to ....
New Homeopathic Drug for Treatment of Multi-Drug Resistant Tuberculosis
Mumbai based researchers have developed a new homeopathic drug which is likely to add value to the ....
Trained Giant Rats Sniff Out Tuberculosis from Sputum Samples in Mozambique
Giant rats are being trained to detect tuberculosis-causing bacteria from rows of sputum samples ......
Cough Symptom Evaluation
Cough is a symptom of a condition usually affecting the respiratory tract. It may be acute or chroni...
Diet in Tuberculosis
Patients with tuberculosis should eat a healthy diet so that they build up their immunity to fight a...
Extra Pulmonary Tuberculosis
Extra pulmonary tuberculosis is infection of tissues and organs other than the lungs by mycobacteriu...
Fever
Fever or Pyrexia is an elevation in normal body temperature. Causes of fever include infections, inj...
Pleural Effusion
Pleural effusion is the accumulation of fluid in the space between the two coverings (pleura) of the...
Screening Tests for Tuberculosis
Tuberculin skin test and Interferon – Release Assays are tests used to screen for tuberculosis....
Silicosis
Silicosis is a lung disease caused by inhalation of crystalline free silica dust. It is characterise...
Stomach Tuberculosis
Abdominal tuberculosis, which is a form of extrapulmonary tuberculosis, affects the gastrointestinal...
Tuberculosis
Tuberculosis, caused by Mycobacterium tuberculosis, primarily affects the lung. It may spread to oth...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use