New Scabies Treatment is More Efficacious: Study

by Ramya Rachamanti on  June 27, 2019 at 6:30 PM Drug News
RSS Email Print This Page Comment bookmark
Font : A-A+

Mass drug administration against scabies decreased the infection rate significantly, according to the results of a comparative trial. These findings were published in the journal New England Journal of Medicine.
New Scabies Treatment is More Efficacious: Study
New Scabies Treatment is More Efficacious: Study

In 2012, the Murdoch Children's Research Institute, the Kirby Institute and the Fiji Ministry for Health, treated almost everyone on a remote Fijian island (716 people) with the oral anti-parasitic drug ivermectin. Scabies, caused by tiny mites, is a debilitating skin condition leading to severe itching. If untreated it can lead to serious bacterial infections, not only of the skin but internal organ systems including the kidney and heart.

Show Full Article


The researchers had previously published their findings at one-year follow up. In the New England Journal of Medicine, the researchers report that 24 months after the treatment, the infection rate was still extremely low, at 3.6 per cent - down 89 per cent on the original figure.

"Mass drug administration has been used to successfully control other important parasitic and bacterial diseases around the world - we have shown it can be used for scabies too, and that its effect is long-lasting," said lead author Dr Lucia Romani from the Kirby Institute at UNSW Sydney.

"The principle of mass drug administration is that regardless of whether or not you know you have scabies, everyone in the community is encouraged to take the medication to kill the mites at the same time and stop them from spreading from person to person."

Professor Andrew Street from the Murdoch Children's Research Institute said the medication, ivermectin, is used against a range of human parasites.

"Ivermectin is recommended by the World Health Organization for the control of common parasitic diseases such as river blindness - over one billion doses have been given and it is known to be very safe," Professor Steer said. "Its creators received the 2015 Noble Prize for Medicine."

Dr Mike Kama, focal person for scabies control in the Fiji Ministry of Health, said in the original trial, the researchers assigned three island communities to different interventions for scabies control: standard care involving treatment of affected individuals and their families using permethrin cream, mass administration of permethrin cream, and mass administration of ivermectin tablets.

"After one year the prevalence of scabies declined in all groups, but by far the most dramatic reduction was in the ivermectin group with a fall in prevalence of 94 per cent," Dr Kama said. "The follow-up study at 24 months shows that this reduction remains sustained over a longer period."

Scabies is widespread in many tropical settings, especially in the Pacific region. The mites thrive in crowded conditions, whether through people living close to each other, or in settings such as schools, or other institutions.



Source: Eurekalert

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
Notify me when reply is posted
I agree to the terms and conditions
Advertisement

More News on:

Scabies 

News A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

News Search

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Stay Connected

  • Available on the Android Market
  • Available on the App Store

News Category

News Archive