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Side effect(s) of Siltuximab


Review the side-effects of Siltuximab as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
The most common side effects of siltuximab are weight gain, infection of the airways, skin rashes and pruritus (itching)

The other side effects are :

  Gastrointestinal:
Constipation, decreased appetite, stomach pain

  Blood:
Low platelet level, fluid accumulation, abnormal blood pressure, high level of uric acid, cholesterol, and triglycerides

  Nervous system:
Headache

  Respiratory:
Throat pain, cough, sneezing, nasal obstruction

  Others:
Dry skin, skin hyperpigmentation, kidney damage

Other Precautions :

Female of childbearing potential are advised to avoid pregnancy by using an effective contraception during the treatment and continue for 3 months after the last infusion of siltuximab.

Patients must be advised to consult the doctor immediately if any new infection or worsening of the existing medical conditions occur.

It is necessary to evaluate the patient’s health status each time before a treatment cycle is given.

Drug Name : Siltuximab

Siltuximab is an immunomodulator used for the treatment of multicentric Castleman’s disease (MCD) in adult patients who are not affected with human immunodeficiency virus (HIV) and human herpesvirus-8 (HHV-8).


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