Lopinavir and Ritonavir generic contains antiretroviral agents, prescribed for HIV-1 infection for adults and children aged above 14 days. It works by decreasing the amount of HIV in the blood by blocking a vital enzyme named protease required for viral multiplication. Update: Ritonavir+ Lopinavir combination is claimed to treat patients with COVID-19. New clinical trial The Efficacy of Lopinavir Plus Ritonavir and Arbidol Against Novel Coronavirus Infection (ELACOI) was started in February 2020 to know the effectiveness of the combination for treating COVID-19. Another trial sponsored by Asan Medical Center, launched in March 2020 is comparing Lopinavir/Ritonavir with Hydroxychloroquine for treating patients with mild coronavirus disease (COVID-19).
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