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Side effect(s) of Hydrochlorothiazide and Spironolactone


Review the side-effects of Hydrochlorothiazide and Spironolactone as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

   Body as a whole
- Weakness.

   Heart
- Low blood pressure.

   Gastrointestinal
- Inflammation of pancreas, jaundice, diarrhea, vomiting, cramping, constipation, gastric irritation, nausea and loss of appetite.

   Blood
- Anemia and decrease in white blood cells/platelets.

   Hypersensitivity
- Shock, respiratory distress including lung inflammation/swelling, photosensitivity, fever, hives, rash and bruising.

   Metabolic
- Electrolyte imbalance.

   Musculoskeletal
- Muscle spasm.

   Central Nervous system
- Vertigo, tingling, dizziness, headache and restlessness.

   Genitourinary
- Kidney failure.

   Skin
- Redness and itching.

   Eye
- Blurred vision.

Other Precautions :

Avoid excess dosage.

Drug Name : Hydrochlorothiazide and Spironolactone

Hydrochlorothiazide and Spironolactone(Aldactazide) generic contains potassium-sparing diuretic and thiazide diuretic, prescribed for essential hypertension and fluid retention caused by various conditions, including heart disease.


Brand Names or Trade Names of Hydrochlorothiazide and Spironolactone

International :


Aldactazide, Spironazide, Spirozide
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