Review the side-effects of Avelumab as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Common: Fatigue , infusion-related reactions that include fever, chills, hypotension and wheezing, peripheral edema
Gastrointestinal: Abdominal pain, diarrhea, nausea, vomiting, constipation
Central nervous system: Headache, dizziness
Respiratory: Cough, difficulty in breathing
Cardiovascular: Increased blood pressure, heartbeat abnormalities, lightheadedness when getting up suddenly from lying or sitting position
Skin: Rashes and itching
Musculoskeletal: Arthralgia and muscle pain
Kidney: Nephritis, renal dysfunction
Immune-reactions: Inflammation of the heart, lung, colon, liver, endocrine organs, diabetes, muscle, brain, blood vessels, psoriasis, arthritis, skin reactions
Others: vision problems, reduced appetite, reduced weight, loss of weight
• Breastfeeding mothers must be informed not to breastfeed during avelumab therapy and also until 1 month after the final dose of avelumab.
If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.
Common: Fatigue , infusion-related reactions that include fever, chills, hypotension and wheezing, peripheral edema
Gastrointestinal: Abdominal pain, diarrhea, nausea, vomiting, constipation
Central nervous system: Headache, dizziness
Respiratory: Cough, difficulty in breathing
Cardiovascular: Increased blood pressure, heartbeat abnormalities, lightheadedness when getting up suddenly from lying or sitting position
Skin: Rashes and itching
Musculoskeletal: Arthralgia and muscle pain
Kidney: Nephritis, renal dysfunction
Immune-reactions: Inflammation of the heart, lung, colon, liver, endocrine organs, diabetes, muscle, brain, blood vessels, psoriasis, arthritis, skin reactions
Others: vision problems, reduced appetite, reduced weight, loss of weight
Other Precautions :
• Patients should be advised to report to an emergency center in case of serious immune-mediated adverse reactions or infusion-related reactions.• Breastfeeding mothers must be informed not to breastfeed during avelumab therapy and also until 1 month after the final dose of avelumab.
