How to Take Regorafenib and Dose of Regorafenib


Find out how to take Regorafenib (drug) and its dose. Describes the best time to take the drug and precautions if any that should be followed.

How to take Regorafenib


How it should be taken  

It comes as a tablet to take by mouth with food.

Dosage & When it is to be taken

PO- The recommended dose is 160mg, once daily for the first 21 days of each 28-day cycle.

When it is not to be taken (Contraindications) 

Why it is prescribed (Indications)  

This medication is a kinase inhibitor, prescribed for metastatic colorectal cancer (CRC) in patients who have been previously treated with fluoropyrimidine- oxaliplatin-and irinotecan-based chemotherapy. It works by helping to stop cancer cells from growing.

Warnings and Precautions  

Caution should be exercised in patients with history of bleeding problems, high blood pressure, heart, liver, or kidney diseases, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Avoid drinking grapefruit juice while taking this medication.
Patient may develop with increased risk of Reversible Posterior Leukoencephalopathy Syndrome (RPLS). If it is so consult with your doctor immediately.

Storage Conditions  

Store it at controlled room temperature (15 to 30C).
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