It comes as a vaginal suppository and as a gel that is inserted into the vagina and solution for injection administered by a health professional. Patient should lie down after insertion of this medication.
Labor induction- As gel: 1 mg, then 1 or 2 mg 6 hr later if neededup to a maximum of 3 mg. As pessary: 3 mg, then 3 mg 6-8 hour later if neededup to a maximum of 6 mg. Suppository: 20mg, inserted into vagina.
Pregnancy termination: It is injected outside the amniotic sac As 100 mcg/ml solution, 1 ml, followed by 1-2 ml at 2-hr intervals according to response.
Prepidil
Dosage & When it is to be taken
Vaginal Dilatation of cervix, induction and augmentation of labor- As gel: 0.5mg, may repeat 6 hr later if needed up to a maximum of 1.5 mg/24 hour.Labor induction- As gel: 1 mg, then 1 or 2 mg 6 hr later if neededup to a maximum of 3 mg. As pessary: 3 mg, then 3 mg 6-8 hour later if neededup to a maximum of 6 mg. Suppository: 20mg, inserted into vagina.
Pregnancy termination: It is injected outside the amniotic sac As 100 mcg/ml solution, 1 ml, followed by 1-2 ml at 2-hr intervals according to response.
When it is not to be taken (Contraindications)
It is contraindicated in patients allergic to prostaglandins, patients with heart, lung, kidney, liver disease or pelvic inflammatory disease.Drug Name : Dinoprostone
This medication is a prostaglandin, prescribed for termination of pregnancy, evacuation of the uterine contents in the missed abortion, labor induction (rarely used), and dilatation of the cervix prior to labor.Brand Names or Trade Names of Dinoprostone
India :
International :
Prepidil