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Ribociclib Interaction with other Drugs


Ribociclib belongs to a class of medications called kinase inhibitors; it inhibits the cyclin-dependent kinase (CDK) 4 and 6.

Ribociclib Interaction with 149 drugs. Find out more in the list below:

Acetyldigitoxin


Acetyldigitoxin may decrease the cardiotoxic activities of Ribociclib.

Alfentanil


The serum concentration of Alfentanil can be increased when it is combined with Ribociclib.

Alprazolam


The serum concentration of Alprazolam can be increased when it is combined with Ribociclib.

Amiodarone


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Amiodarone.

Anagrelide


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Anagrelide.

Ancestim


The risk or severity of cytotoxicity can be increased when Ancestim is combined with Ribociclib.

Anhydrous Tacrolimus


The serum concentration of Tacrolimus can be increased when it is combined with Ribociclib.

Apalutamide


The serum concentration of Ribociclib can be decreased when it is combined with Apalutamide.

Aprepitant


The serum concentration of Aprepitant can be increased when it is combined with Ribociclib.

Arsenic Trioxide


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Arsenic trioxide.

Astemizole


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Astemizole.

Atazanavir


The serum concentration of Ribociclib can be increased when it is combined with Atazanavir.

Atorvastatin


The serum concentration of Atorvastatin can be increased when it is combined with Ribociclib.

Avanafil


The serum concentration of Avanafil can be increased when it is combined with Ribociclib.

Azithromycin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Azithromycin.

Bepridil


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Bepridil.

Bevacizumab


Bevacizumab may increase the cardiotoxic activities of Ribociclib.

Bevacizumab-Awwb


Bevacizumab may increase the cardiotoxic activities of Ribociclib.

Boceprevir


The serum concentration of Ribociclib can be increased when it is combined with Boceprevir.

Budesonide


The serum concentration of Budesonide can be increased when it is combined with Ribociclib.

Buspirone


The serum concentration of Buspirone can be increased when it is combined with Ribociclib.

Cabazitaxel


The risk or severity of adverse effects can be increased when Cabazitaxel is combined with Ribociclib.

Carbamazepine


The serum concentration of Ribociclib can be decreased when it is combined with Carbamazepine.

Ceritinib


The serum concentration of Ribociclib can be increased when it is combined with Ceritinib.

Chloroquine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Chloroquine.

Chlorpromazine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Chlorpromazine.

Cilostazol


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Cilostazol.

Ciprofloxacin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Ciprofloxacin.

Cisapride


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Cisapride.

Citalopram


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Citalopram.

Clarithromycin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Clarithromycin.

Cobicistat


The serum concentration of Ribociclib can be increased when it is combined with Cobicistat.

Cocaine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Cocaine.

Colchicine


The serum concentration of Colchicine can be increased when it is combined with Ribociclib.

Conivaptan


The serum concentration of Conivaptan can be increased when it is combined with Ribociclib.

Curcumin


The serum concentration of Ribociclib can be increased when it is combined with Curcumin.

Cyclophosphamide


Cyclophosphamide may increase the cardiotoxic activities of Ribociclib.

Cyclophosphamide Anhydrous


Cyclophosphamide may increase the cardiotoxic activities of Ribociclib.

Darifenacin


The serum concentration of Darifenacin can be increased when it is combined with Ribociclib.

Darunavir


The serum concentration of Ribociclib can be increased when it is combined with Darunavir.

Dasatinib


The serum concentration of Dasatinib can be increased when it is combined with Ribociclib.

Dasatinib Anhydrous


The serum concentration of Dasatinib can be increased when it is combined with Ribociclib.

Deslanoside


Deslanoside may decrease the cardiotoxic activities of Ribociclib.

Digitoxin


Digitoxin may decrease the cardiotoxic activities of Ribociclib.

Digoxin


Digoxin may decrease the cardiotoxic activities of Ribociclib.

Disopyramide


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Disopyramide.

Docetaxel


The risk or severity of adverse effects can be increased when Docetaxel is combined with Ribociclib.

DOCETAXEL ANHYDROUS


The risk or severity of adverse effects can be increased when Docetaxel is combined with Ribociclib.

Dofetilide


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Dofetilide.

Domperidone


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Domperidone.

Donepezil


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Donepezil.

Dronedarone


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Dronedarone.

Droperidol


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Droperidol.

Ebastine


The serum concentration of Ebastine can be increased when it is combined with Ribociclib.

Eletriptan


The serum concentration of Eletriptan can be increased when it is combined with Ribociclib.

Eliglustat


The serum concentration of Eliglustat can be increased when it is combined with Ribociclib.

Enzalutamide


The serum concentration of Ribociclib can be decreased when it is combined with Enzalutamide.

Eplerenone


The serum concentration of Eplerenone can be increased when it is combined with Ribociclib.

Erythromycin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Erythromycin.

Escitalopram


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Escitalopram.

Everolimus


The serum concentration of Everolimus can be increased when it is combined with Ribociclib.

Felodipine


The serum concentration of Felodipine can be increased when it is combined with Ribociclib.

Flecainide


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Flecainide.

Fluconazole


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Fluconazole.

Fosphenytoin


The serum concentration of Ribociclib can be decreased when it is combined with Fosphenytoin.

Gatifloxacin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Gatifloxacin.

Gatifloxacin Anhydrous


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Gatifloxacin.

Grepafloxacin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Grepafloxacin.

Halofantrine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Halofantrine.

Haloperidol


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Haloperidol.

Hypoxis hemerocallidea root extract


The serum concentration of Ribociclib can be decreased when it is combined with St. John's Wort.

Ibrutinib


The serum concentration of Ibrutinib can be increased when it is combined with Ribociclib.

Ibutilide


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Ibutilide.

Idelalisib


The serum concentration of Ribociclib can be increased when it is combined with Idelalisib.

Indinavir


The serum concentration of Ribociclib can be increased when it is combined with Indinavir.

INDINAVIR ANHYDROUS


The serum concentration of Ribociclib can be increased when it is combined with Indinavir.

Itraconazole


The serum concentration of Ribociclib can be increased when it is combined with Itraconazole.

Ketoconazole


The serum concentration of Ribociclib can be increased when it is combined with Ketoconazole.

Levofloxacin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Levofloxacin.

Levofloxacin Anhydrous


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Levofloxacin.

Levomethadyl


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Levomethadyl Acetate.

Lomitapide


The serum concentration of Lomitapide can be increased when it is combined with Ribociclib.

Lopinavir


The serum concentration of Ribociclib can be increased when it is combined with Lopinavir.

Lovastatin


The serum concentration of Lovastatin can be increased when it is combined with Ribociclib.

Lumacaftor


The serum concentration of Ribociclib can be decreased when it is combined with Lumacaftor.

Lurasidone


The serum concentration of Lurasidone can be increased when it is combined with Ribociclib.

Maraviroc


The serum concentration of Maraviroc can be increased when it is combined with Ribociclib.

Mesoridazine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Mesoridazine.

Methadone


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Methadone.

Methotrimeprazine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Methotrimeprazine.

Midazolam


The serum concentration of Midazolam can be increased when it is combined with Ribociclib.

Midostaurin


The serum concentration of Ribociclib can be decreased when it is combined with Midostaurin.

Mitotane


The serum concentration of Ribociclib can be decreased when it is combined with Mitotane.

Moxifloxacin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Moxifloxacin.

Naloxegol


The serum concentration of Naloxegol can be increased when it is combined with Ribociclib.

Nefazodone


The serum concentration of Ribociclib can be increased when it is combined with Nefazodone.

Nelfinavir


The serum concentration of Ribociclib can be increased when it is combined with Nelfinavir.

Nevirapine


The serum concentration of Ribociclib can be decreased when it is combined with Nevirapine.

Nisoldipine


The serum concentration of Nisoldipine can be increased when it is combined with Ribociclib.

Ondansetron


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Ondansetron.

Ouabain


Ouabain may decrease the cardiotoxic activities of Ribociclib.

Ovine Digoxin Immune Fab


Digoxin Immune Fab (Ovine) may decrease the cardiotoxic activities of Ribociclib.

Oxaliplatin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Oxaliplatin.

Paclitaxel


The risk or severity of adverse effects can be increased when Paclitaxel is combined with Ribociclib.

Papaverine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Papaverine.

Pentamidine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Pentamidine.

Pentobarbital


The serum concentration of Ribociclib can be decreased when it is combined with Pentobarbital.

Phenobarbital


The serum concentration of Ribociclib can be decreased when it is combined with Phenobarbital.

Phenytoin


The serum concentration of Ribociclib can be decreased when it is combined with Phenytoin.

Pimozide


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Pimozide.

Posaconazole


The serum concentration of Ribociclib can be increased when it is combined with Posaconazole.

Primidone


The serum concentration of Ribociclib can be decreased when it is combined with Primidone.

Probucol


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Probucol.

Procainamide


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Procainamide.

Propofol


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Propofol.

Proscillaridin


Proscillaridin may decrease the cardiotoxic activities of Ribociclib.

Quetiapine


The serum concentration of Quetiapine can be increased when it is combined with Ribociclib.

Quetiapine fumarate


The serum concentration of Quetiapine can be increased when it is combined with Ribociclib.

Quinidine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Quinidine.

Rifabutin


The serum concentration of Ribociclib can be decreased when it is combined with Rifabutin.

Rifampin


The serum concentration of Ribociclib can be decreased when it is combined with Rifampicin.

Rifapentine


The serum concentration of Ribociclib can be decreased when it is combined with Rifapentine.

Rilpivirine


The serum concentration of Rilpivirine can be increased when it is combined with Ribociclib.

Rivaroxaban


The serum concentration of Rivaroxaban can be increased when it is combined with Ribociclib.

Roxithromycin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Roxithromycin.

Saquinavir


The serum concentration of Ribociclib can be increased when it is combined with Saquinavir.

Saquinavir Mesylate


The serum concentration of Ribociclib can be increased when it is combined with Saquinavir.

Sevoflurane


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Sevoflurane.

Sildenafil


The serum concentration of Sildenafil can be increased when it is combined with Ribociclib.

Simvastatin


The serum concentration of Simvastatin can be increased when it is combined with Ribociclib.

Sirolimus


The serum concentration of Sirolimus can be increased when it is combined with Ribociclib.

Sotalol


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Sotalol.

Sparfloxacin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Sparfloxacin.

ST. JOHN'S WORT EXTRACT


The serum concentration of Ribociclib can be decreased when it is combined with St. John's Wort.

Sulpiride


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Sulpiride.

Tacrolimus


The serum concentration of Tacrolimus can be increased when it is combined with Ribociclib.

Tadalafil


The serum concentration of Tadalafil can be increased when it is combined with Ribociclib.

Telaprevir


The serum concentration of Ribociclib can be increased when it is combined with Telaprevir.

Telithromycin


The serum concentration of Ribociclib can be increased when it is combined with Telithromycin.

Terfenadine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Terfenadine.

Terlipressin


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Terlipressin.

Thioridazine


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Thioridazine.

Ticagrelor


The serum concentration of Ticagrelor can be increased when it is combined with Ribociclib.

Tolvaptan


The serum concentration of Tolvaptan can be increased when it is combined with Ribociclib.

Trastuzumab


Trastuzumab may increase the cardiotoxic activities of Ribociclib.

Triazolam


The serum concentration of Triazolam can be increased when it is combined with Ribociclib.

Vandetanib


The risk or severity of QTc prolongation can be increased when Ribociclib is combined with Vandetanib.

Vardenafil


The serum concentration of Vardenafil can be increased when it is combined with Ribociclib.

Voriconazole


The serum concentration of Ribociclib can be increased when it is combined with Voriconazole.

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