Carbamazepine - Drug Toxicity

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Latest prescription information about Carbamazepine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Drug Name : Carbamazepine

Indication : Carbamazepine is a first line antiepileptic drug for generalized and partial seizures. The drug is used to control pain in trigeminal neuralgia and in treatment of bipolar effective disorder.


Physiology : The addition of anticonvulsants which decrease carbamazepine level may cause seizures. Drugs which increases the concentration of carbamazepine causes delayed toxicity.

Normal Values : 8-12 µg/ml (25-51 µmol/L)
Critical Values : Higher than normal values causes central nervous system toxicity


Test Method : Enzyme Immunoassay, Gas chromotography, High Performance Liquid Chromatography(HPLC).


Side effects : Frequent side effects include drowsiness, ataxia (lack of muscle control during voluntary movements like walking), blurred vision, nausea, vomiting and skin rash. Other adverse effects include reduced blood counts and water retention. Toxic doses can cause seizures and cardiovascular collapse.

Related Drugs : Theophylline, Valproic acid, Warfarin.

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