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Drug information on Nex 400 (Naloxone) from Neon Laboratories Limited

Nex 400

  Injection
Neon Laboratories Limited
Generic : Naloxone
 85.50
400mcg
1ml

Drug Name : Naloxone

Naloxone(arcan) generic Nex 400 is an opioid antagonist, prescribed for morphine and most other opioid poisoning. It is used to reverse respiratory depression in the newborn when the mother was administered opioids during labor. It is also indicated for the diagnosis of suspected acute opioid over dosage. It may also be useful in other conditions such as to increase blood pressure in certain types of shock, and central nervous system injuries.
More Info about Naloxone


Dhanalakshmi Chinnuswamy
Further Checked by The Medindia Medical Review Team on February, 2, 2017
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Medical Condition(s) for which Nex 400 may be prescribed


Side effects of Nex 400

Adverse effects with naloxone occur when it is given to postoperative patients or due to sudden reversal of opioid depression or sudden withdrawal in opioid dependence.

  Potentially Fatal: Severe cardiopulmonary effects in postoperative patients, most frequently in those with preexisting heart disease.

  Heart: Fluid accumulation in the lungs, cardiac arrest or failure, fast heart rate.

  Gastrointestinal: Vomiting, nausea.

  Central Nervous System: Convulsions, tingling, agitation, hallucination, tremulousness.

  Respiratory : Difficulty in breath, respiratory depression.

  Skin : Injection site reactions, sweating.

Dosage & When it is to be taken (Indications)

Adult: Opioid over dosage- The recommended dose is 0.4- to 0.8mg, IV, repeat if needed at 2-3 min intervals. Consider over dosage with other drugs if there is no response after a total of 10 mg has been given.

How to use Nex 400?

It is usually given as an injection by a doctor or hospital staff.

When is Nex 400 not to be taken? (Contraindications)

Hypersensitivity.

Warnings and Precautions for Nex 400

It may make you drowsy. Do not drive a car or operate machineries while taking this medication.

•Caution needed for patients physically dependent on opioids, or who have received large doses of opioids (acute withdrawal syndrome may be precipitated), pregnancy and breastfeeding.

Other Precautions for Nex 400

Do not change the dosage without your doctor's advice.

Storage Conditions for Nex 400

Injection: Store it at room temperature (25°C). Protect from light.



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