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Mipomersen Injection - Indications, Dosage, Side Effects and Precautions

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Information about Mipomersen Injection

Generic Name : Mipomersen Injection
Latest prescription information about Mipomersen Injection. Learn its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
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Trade Names/Brand Names of Mipomersen Injection

International- Kynamro.
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Why is Mipomersen Injection Prescribed? (Indications)

This medication is a cholesterol-reducing agent (oligonucleotide inhibitor- an orphan drug), prescribed for hypercholesterolemia. 
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When should Mipomersen Injection not be taken? (Contraindications)

Contraindicated in patients with moderate or severe liver impairment, and known hypersensitivity.

What is the dosage of Mipomersen Injection?

SC- The recommended dose is 200 mg once weekly.

How should Mipomersen Injection be taken?

It comes as a solution for injection to be administered by a healthcare provider under the skin.

What are the warnings and precautions for Mipomersen Injection?

• Caution should be exercised in patients with history of kidney or liver problems, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.

Monitor blood cholesterol level regularly while taking this medication.

What are the side effects of Mipomersen Injection?

  Most Common: Injection site reactions, flu-like symptoms, nausea, headache and elevations in serum transaminases.
   Heart : Chest pain, palpitations, high blood pressure.
   Gastrointestinal : Vomiting, abdominal pain.
   Liver : Abnormal liver function and elevation in liver enzymes.
   Miscellaneous : Fatigue, fever, chills, swelling in the extremities, musculoskeletal pain, and sleeplessness.

What are the other precautions for Mipomersen Injection?

Avoid excess dosage.

What are the storage conditions for Mipomersen Injection?

Store it in a refrigerator (2C to 8C).



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