This medication is a cholesterol-reducing agent (oligonucleotide inhibitor- an orphan drug), prescribed for hypercholesterolemia. 

Contraindicated in patients with moderate or severe liver impairment, and known hypersensitivity.

SC- The recommended dose is 200 mg once weekly.

It comes as a solution for injection to be administered by a healthcare provider under the skin.

• Caution should be exercised in patients with history of kidney or liver problems, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• Monitor blood cholesterol level regularly while taking this medication.

•  Most Common: Injection site reactions, flu-like symptoms, nausea, headache and elevations in serum transaminases.
•   Heart : Chest pain, palpitations, high blood pressure.
•   Gastrointestinal : Vomiting, abdominal pain.
•   Liver : Abnormal liver function and elevation in liver enzymes.
•   Miscellaneous : Fatigue, fever, chills, swelling in the extremities, musculoskeletal pain, and sleeplessness.

Avoid excess dosage.

Store it in a refrigerator (2°C to 8°C).