This medication is a cholesterol-reducing agent (oligonucleotide inhibitor- an orphan drug), prescribed for hypercholesterolemia.
Contraindicated in patients with moderate or severe liver impairment, and known hypersensitivity.
SC- The recommended dose is 200 mg once weekly.
It comes as a solution for injection to be administered by a healthcare provider under the skin.
Caution should be exercised in patients with history of kidney or liver problems, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Monitor blood cholesterol level regularly while taking this medication.
Injection site reactions, flu-like symptoms, nausea, headache and elevations in serum transaminases.
Heart : Chest pain, palpitations, high blood pressure.
Gastrointestinal : Vomiting, abdominal pain.
Liver : Abnormal liver function and elevation in liver enzymes.
Miscellaneous : Fatigue, fever, chills, swelling in the extremities, musculoskeletal pain, and sleeplessness.
Avoid excess dosage.
Store it in a refrigerator (2°C to 8°C).
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