This medication is a cholesterol-reducing agent (oligonucleotide inhibitor- an orphan drug), prescribed for hypercholesterolemia.
Contraindicated in patients with moderate or severe liver impairment, and known hypersensitivity.
SC- The recommended dose is 200 mg once weekly.
It comes as a solution for injection to be administered by a healthcare provider under the skin.
• Caution should be exercised in patients with history of kidney or liver problems, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
• Monitor blood cholesterol level regularly while taking this medication.
• Most Common:
Injection site reactions, flu-like symptoms, nausea, headache and elevations in serum transaminases.
• Heart : Chest pain, palpitations, high blood pressure.
• Gastrointestinal : Vomiting, abdominal pain.
• Liver : Abnormal liver function and elevation in liver enzymes.
• Miscellaneous : Fatigue, fever, chills, swelling in the extremities, musculoskeletal pain, and sleeplessness.
Avoid excess dosage.
Store it in a refrigerator (2°C to 8°C).
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