Pallavi Singh
Written & Compiled by Pallavi Singh, M. Pharmacy (Pharmacy Practice) , Dhanalakshmi Chinnuswamy
Medically Reviewed by The Medindia Medical Review Team on Nov 16, 2011
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General Information on Mecobalamin

Generic Name : Mecobalamin

Latest prescription information about Mecobalamin. Learn its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Vitamins

Trade Names/Brand Names of Mecobalamin

India : 


International : 

Humabala, Matey , Amcobal , Beecoba M, Berthyco, Chiokinate, Cobal, Cobametin, Cobolmin, Comesgen, Cynodex, Cynomin, Econvita, Ethigobal, Hitocobamin, Isecobamin, Kalmeco, Lanabal, Lapibal, Mecobal, M Read more..

Other Name(s) of Mecobalamin

Methylcobalamin, MeCbl, MeB12

Overview of Mecobalamin

Methylcobalamin is the activated form of vitamin B12 and an essential nutrient for the body.

Why is Mecobalamin Prescribed? (Indications)

MeCbl is now prescribed for the treatment of vitamin B12 deficiency and is slowly replacing the traditional B12 formulations like cyanocobalamin and hydroxocobalamin.

MeCbl is essential for the normal functioning of the brain and nervous system and the formation of blood.

It is used to treat anemia, Alzheimer’s disease, peripheral neuropathy, diabetic neuropathy, rheumatoid arthritis, and probably amyotrophic lateral sclerosis.  

When should Mecobalamin not to be taken? (Contraindications)

Methylcobalamin is contraindicated if the patients are allergic to the drug.

What is the dosage of Mecobalamin?

The recommended dose of the drug is 500 mcg tablets to start with.

Peripheral neuropathy - The recommended dose is 1,500 mcg/day in 3 divided doses.

How should Mecobalamin be taken?

Methylcobalamin comes as a tablet to take by mouth, with or without food.

It is also available as sprays, sublingual supplements and liquid forms for those who cannot digest the tablet form well.

Mecobalamin also comes as a solution for injection to be administered by a healthcare provider into the vein or muscle.

What are the warnings and precautions for Mecobalamin?

• Caution should be exercised in patients with history of liver disease, any allergy, during pregnancy and breastfeeding.

• Consult the doctor if you experience any allergic reaction.

What are the side effects of Mecobalamin?

   Oral : Loss of appetite, nausea, vomiting and diarrhea.

   Parenteral : Rash, headache, hot sensation, sweating, itching , swelling and pain/induration at injection site.

What are the other precautions for Mecobalamin?

Avoid excess dosage.

Methylcobalamin might need to be taken with adenosylcobalamin for maximum benefit.

Please check with your doctor before taking these drug combination.

What are the Drug Interactions of Mecobalamin?

Not known.

What are the storage conditions for Mecobalamin?

Store it at room temperature (15 to 25°C).

Last Updated : Jun 2018

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sankaraiah, India

I am a type 2 diabetic with dislipidemia and peripheral neuropathy for the past three years.I am on medication of Glimiperide 1mg, Atorvastatin 10mg, and meoxon respectively.My sugar levels and Lipid levels are under control but my PN is not in control.What shall I do to bring my burning feet, pins and needle under control.

gaganvihari, India

dear sir i have diabetic type 2 person which vitamin tablet for me

PatrickJB, Indonesia

My doc diagnosed me as suffering from Sudden Sensorineural Hearing Loss. At first I thought it was the ear nerve problem but after 7 days I had recovered/felt the tingling feeling in the ear if I make a probe into the ear canal using cotton swab. No more nausea, no more dizziness; just a little walking imbalances or when I moves abruptly.

P.S. I don't know what exactly is my sickness as my doc simply said it was Vertigo-SHL.

It has been 12 days now (4 days in the hospital) and I still had the 'fullness' feeling (which comes and go) inside my right ear. I am on the 1st of 4 treatment/injection of Kalmeco-Mecobalamin Made in Pakistan. How good is this medicine for my treatment? Is there any other alternative/better medication?

What will be the chances of regaining full hearing in my said case?

P.S. My ear drum/canal are ok. I was never sick, age 54. Health condition (blood pressure, etc are ok)

Sitalaxmi, India

I want to know taking the MecoNeuron-OD 1500 mcg 1 tab daily as
per Dr. advise whether it is harmful to a Diabetic patient.
Please let me know. thanks.

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