Information about Mechlorethamine HCl

Generic Name : Mechlorethamine HCl
Up-to-date prescription details regarding Mechlorethamine HCl are provided here.

Pronunciation : meh-klor-ETH-ah-meen

Learn the correct pronunciation of the Mechlorethamine HCl, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Trade Names/Brand Names of Mechlorethamine HCl

International :

Mustargen

Why is Mechlorethamine HCl Prescribed? (Indications)

This medication is an anti-neoplastic agent, prescribed for Hodgkin's disease, non-Hodgkin's lymphoma along with other medications. It is also used as palliative chemotherapy in lung and breast cancers. It slows or stops the growth of cancer cells in the body.

When should Mechlorethamine HCl not be taken? (Contraindications)

Contraindicated in patients with infectious disease and known hypersensitivity.

What is the dosage of Mechlorethamine HCl?

IV- A total dose of 0.4 mg/kg usually is given either as a single dose or in divided doses of 0.1 to 0.2 mg/kg per day.

How should Mechlorethamine HCl be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Mechlorethamine HCl?

• It should not be administered via intradermal, subcutaneous, IM, intraarterial, or oral administration.

• Caution should be exercised in patients with blood/bleeding disorders, gout, current infection, kidney disease, liver disease, radiation treatment, any allergy, during pregnancy and breastfeeding.

• It may reduce platelet counts; avoid injury or bruising.

• It may cause drowsiness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption while taking this medication.

What are the side effects of Mechlorethamine HCl?

Skin - Hair loss, redness of the skin, herpes zoster; skin eruptions.
Eye and ENT - Diminished hearing, ringing in the ear, and fainting.
Gastrointestinal - Loss of appetite, diarrhea, nausea, vomiting.
Genitourinary - Decreased sperm count, impaired spermatogenesis, absence of menstrual period, delayed menses, increase in blood urea.
Blood - Bone marrow suppression and decrease in blood cells count.
Liver - Jaundice.
Miscellaneous - Chromosomal abnormalities, anaphylaxis.