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Isatuximab - Indications, Dosage, Side Effects and Precautions

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Information about Isatuximab

Generic Name : Isatuximab
Up-to-date prescription details regarding Isatuximab are provided here.

Pronunciation : I-suh-TUK-sih-mab

Learn the correct pronunciation of the Isatuximab, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


Trade Names/Brand Names of Isatuximab

India :


Sarclisa

Overview of Isatuximab

Isatuximab is an anticancer agent indicated for the treatment of adults with multiple myeloma. Mutiple myeloma is a type of cancer that affects the plasma cells of the white blood cell.
It should be used along with chemotherapy drug pomalidomide with steroid -dexamethasone among patients who have received at least two prior chemotherapies with lenalidomide and a proteasome inhibitor.

Why is Isatuximab Prescribed? (Indications)

Isatuximab is an anticancer agent indicated for the treatment of adults with multiple myeloma.

When should Isatuximab not be taken? (Contraindications)

Patients allergic to Isatuximab

What is the dosage of Isatuximab?

Isatuximab is available as an injection:
10mg/kg body weight
20mg/kg body weight

How should Isatuximab be taken?

The recommended dosage is 10 mg/kg body weight, given as an intravenous infusion every week for 4 weeks followed by every 2 weeks along with pomalidomide and dexamethasone.
It should be given for 28 days.

Missed a Dose?

If a planned dose of Istauximab is missed, administer the dose as soon as possible and adjust the treatment schedule accordingly, maintaining the treatment interval.

What are the warnings and precautions for Isatuximab?

• Pregnant and lactating women should use this drug.

• If a lactating woman uses the drug, breastfeeding should be avoided.

• Safety of usage was not established in children.

What are the side effects of Isatuximab?

•General: Infusion-related reactions, low white blood cell count
•Digestive: Nausea, vomiting, diarrhea
•Respiratory: Pneumonia, upper respiratory tract infection, dyspnea, or difficulty in breathing

What are the other precautions for Isatuximab?

•Infusion-related reactions can occur. If a reaction occurs, the infusion must be discontinued.
•In women who are in child bearing age, proper contraceptives should be used as it can cause fetal harm
•Monitor blood cell counts periodically during treatment, especially neutrophil (A kind of white blood cell)
•Monitor patients for the development of second primary malignancies (cancers).

What are the storage conditions for Isatuximab?

Store vials refrigerated in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton to protect from light. Do not freeze. Do not shake
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