Pallavi Singh
Written & Compiled by Pharmacist Pallavi Singh, M. Pharmacy (Pharmacy Practice)
Suchitra Chari
Medically Reviewed by Suchitra Chari, M.S. M.Sc.
Last Updated on Feb 20, 2018
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General Information on Enbucrilate

Generic Name : Enbucrilate

Pronunciation : En- Bu-cri-late

Latest prescription information about Enbucrilate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Therapeutic Classification : Surgical Aid

Trade Names/Brand Names of Enbucrilate

Overview of Enbucrilate

Enbucrilate or n-butyl 2-cyanoacrylate is used as a surgical tissue adhesive to seal wounds, lacerations of the skin and surgical incisions.

Why is Enbucrilate Prescribed? (Indications)

Enbucrilate or n-butyl 2-cyanoacrylate is used as a surgical tissue adhesive to seal wounds, lacerations of the skin and surgical incisions. It is a safe and painless alternative to sutures and staples.
Butyl cyanoacrylate is a tissue glue that is applied as a liquid monomer solution to wet tissue; it polymerizes in seconds turning into a solid state when exposed to water-containing substances like human tissue. It thus terminates the bleeding.

It is slowly biodegradable and used in all kinds of surgery, including dental where it is used along with deep dermal sutures.
In gastroenterology, it is used to treat bleeding from vascular structures, specifically gastric varices (dilated or enlarged submucosal veins in the stomach that can cause severe bleeding in the upper gastrointestinal tract).
Enbucrilate is injected with a catheter needle inserted into the gastric varices through an endoscope.

Butyly cyanocrylate has also been used to treat malformations or abnormal connections between the arteries and veins in the brain and the spine where the adhesive is applied into the abnormality through angiography. 

When should Enbucrilate not to be taken? (Contraindications)

It is contraindicated if the patient is allergic to the drug, or has contaminated wounds, bites, punctures or crushed wounds.

What is the dosage of Enbucrilate?

The recommended dosage of the drug is 0.25ml/1ampoule.

How should Enbucrilate be taken?

Enbucrilate should be used along but not in place of stitches to close the wound.

What are the warnings and precautions for Enbucrilate?

The product can only be used by a registered medical practitioner or under the guidance of a doctor
Keep wounds dry after closure
Use with caution in pregnant women
Use the drug carefully in children
Do not use any topical medications to cover the wound after administration

What are the side effects of Enbucrilate?

Skin: Localized skin sensitization or irritation, inflammation, and chronic pain

What are the other precautions for Enbucrilate?

Follow the instruction given by the doctor carefully
Extra caution has to be taken to avoid contact with gloves, and surgical instruments during application as the glue can bond to many surfaces.
Take care while introducing the product into eyes as it can bond the eyelids.

What are the Drug Interactions of Enbucrilate?

Not known

What are the storage conditions for Enbucrilate?

Store the drug at room temperature.
Keep it away from the reach of children.

Last Updated : 2/20/2018

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