Pralidoxime - Drug Information

Generic Name : Pralidoxime
Pronunciation : PRAL i DOX eem

ICD Code : Y57.2 | Therapeutic Classification : Anticholinesterase Antidote

Trade Name(s) :

India - Adipam, Pam -up, 2 -Pam-1, Neopam, Aldopam, Redpam, Clopam (500 mg), Lyphe (500 mg), Lyphe (1000 mg), Clopam (1 gm), Nispam, Lyphe, Unipam, CBC -Pam


International - Protopam Chloride.

Why is Pralidoxime Prescribed? (Indications)

This medication is an antidote, prescribed for organophosphorous poisoning. But is not effective as an antidote for all types of pesticide poisonings.

When should Pralidoxime not to be taken? (Contraindications)

Contraindications in patients with known hypersensitivity to the drug and Carbamate pesticide poisoning.

What is the dosage of Pralidoxime?

Adult: IV/IM- Used in combination with atropine. The recommended dose is 1-2 g, repeat dose after 1 hour, then 8-12 hourly if needed.

How should Pralidoxime be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein, muscle or under the skin.

What are the warnings and precautions for Pralidoxime?

* Caution should be exercised in patients with history of myasthenia gravis, kidney disease, during pregnancy and breastfeeding.
* Monitor breathing, blood pressure, oxygen levels, kidney function regularly while taking this medication.
* It may cause drowsiness, blurred vision, or dizziness, do not drive a car or operate machinery while taking this medication.

What are the side effects of Pralidoxime?

Most Common - Blurred vision, double vision, impaired accommodation, dizziness, headache, drowsiness, nausea, muscle weakness, and fast heart rate.

What are the other precautions for Pralidoxime?

* Avoid excess dosage.

What are the storage conditions for Pralidoxime?

Store it at room temperature (20�-25�C).