Chronic Granulomatous Disease (CGD)

Rating : 12345
Rate This Article : 1 2 3 4 5
RSS Email Print This Page Comment

About

Advertisement
Chronic granulomatous disease (also known as “Bridges–Good syndrome," "Chronic granulomatous disorder," and "Quie syndrome") is an inherited disorder in which immune system cells called phagocytes malfunction.

In Chronic Granulomatous Disease (CGD) the white blood cells are unable to produce activated O2 compounds (or anti-oxidants), which normally help a person to fight against infection. Thus, this leads to recurrent life-threatening bacterial and fungal infections. There occurs an excessive accumulation of immune cells into aggregates called granulomas.
Advertisement

Diagnosis is done using a test called flow cytometric respiratory burst assay.

Chronic Granulomatous Disease

Treatment is with antibiotics, antifungal drugs, and interferon-.

The disease was first described in the 1950s as “a fatal granulomatosus of childhood". More than half of cases of chronic granulomatous disease are transmitted genetically as an X-linked recessive trait. CGD thus occurs only in males. Most of the patients with CGD present during the first 5 years of life. In the rest inheritance is autosomal recessive. No racial predilection is known.
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
* Your comment can be maximum of 2500 characters
Notify me when reply is posted
I agree to the terms and conditions
MaryHurley Wednesday, March 16, 2011

Very good article. We have an international support group for CGD. CGD Association c/o Mary Hurley cgda@socal.rr.com www.cgdassociation.org We do not have any CGD patients from India on our database. Please forward this information to your CGD patients as it would be good to link patients from India with other patients from India. Thanks, Mary Hurley

Advertisement
View All

Related Links

Show More Related Topics

Advertisement

Health Topics A - Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Medindia Health Topics Search

Genetic Disorders

Medindia Newsletters

Subscribe to our Free Newsletters!

Terms & Conditions and Privacy Policy.

Advertisement

Advertisement
Advertisement

Doctor Search

Stay Connected

  • Available on the Android Market
  • Available on the App Store

Facebook