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DNA Fingerprinting

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About

Unlike a conventional fingerprint that occurs only on the fingertips and can be altered by surgery, a DNA fingerprint is the same for every tissue, and organ of a person. It cannot be altered by any known treatment.
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Fingerprinting with ink and paper, based on fingertip ridge patterns is the standard method for personal identification. Fingerprints are constant throughout life, fingerprints can be used to distinguish one person from any other. Similarly the DNA of every individual is also unique in its own way. Actually the method should be called simply DNA printing or DNA typing since it has nothing to do with the fingers. The degree of variation in bands from one person to another is so large that the theoretical probability that the bands seen in one individual are present in another unrelated individual may be in millions. The advantages over fingerprints are numerous. DNA can be isolated from any part of the body, skin cells, blood or blood stains or semen.

DNA Finger Printing


The human DNA is different from other living organisms Hence blood of an animal will have different DNA sequence and characteristics. Hence DNA fingerprinting is a very quick way to compare the DNA sequences of any two living organisms.

However some of the disadvantages of DNA fingerprinting are:
  • It requires further standardization and quality control, to be universally accepted as a tool.
  • There are only a few reliable labs around the world that can give accurate results.
  • There is also 1 in 50 billion chance of two DNA sequence being similar.
Application of DNA Fingerprinting
  1. It is currently employed in paternity disputes
  2. Identification of bodies of soldiers killed in war. It was also used for identification of the body of Nazi physician Joseph Mengele, the so-called "Angel of Death." In fact it has been used a to reunite a kid lost in the Tsunami with his parents.
  3. To diagnose inherited disorders in both prenatal and newborn babies, like:
    1. Cystic fibrosis
    2. Sickle cell anemia
    3. Thalassemia
    4. Hemophilia
    5. Huntington's disease
    6. Alzheimer's Disease (Familial Type)
    7. Huntington's Chorea
    8. Marfan's syndrome
Many other similar disorders can be diagnosed
  • Biological Evidence to Identify Criminals: Where fingerprints are not available but biological specimens are available like blood or semen stains, hair, or items of clothing at the scene of the crime then these items may prove to be valuable sources of DNA of the criminal. Since the year 1987, innumerable cases have been solved with the help of DNA fingerprint evidence.
  • Personal Identification - DNA maybe the best way to identify a person as all body tissues and organs contain the same DNA type. The specimen required also is very small. In fact the US army has been doing DNA fingerprinting of all its soldiers and has a huge databank. The DNA method for personal identification is far superior to the dental records and blood typing methods that were popularly being used.
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why do we use VNTR's inspite of bulk DNA ? How VNTR's are related to introns ?
Shivani17 Tuesday, August 30, 2011
dna can detect criminals such as stealing and more
qq101 Wednesday, June 16, 2010
YAH IT CAN DETECT. AND IS VERY HELPFUL FOR POLICE.
guest Wednesday, June 23, 2010
please tell me method of dnafingerprinting or its mechanism...
dimple payal Wednesday, November 26, 2008
DNA fingerprinting uses electorphoresis, very basically samples are put into aragose gel, through which a current is passed causing the samples to move through the gel. the smaller parts of DNA move faster so the DNA sample is broken out into bands according to its makeup, the bands of different DNA samples can then be compared. i think that is right, if you search gel electrophoresis there a few sites that can tell you more
guest Wednesday, August 19, 2009
Which situations[ biological]donot permit to implement DNA analysis/fingerprinting? That is even the cells are dead [ recent or thousands of year old-Mummy],can DNA be extracted and evaluated?
guest Tuesday, May 15, 2007
what does a mummy have to do with anything??
guest Thursday, January 8, 2009
yes
qq101 Wednesday, June 16, 2010

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