Indian snakeroot (Sarpagandha)- to Lower High Blood Pressure / Hypertension
Part used: root
Although this herb is best known for treating high blood pressure, it is used in Indian folk medicine as remedy for mental disorders too. The role of reserpine in reducing blood pressure can be described as follows. Dopamine, epinephrine (adrenaline), and noradrenaline are a group of hormones (neurotransmitters) known collectively as catecholamines. These are produced in the adrenal glands and are released into the bloodstream in response to physical or emotional stress. Noradrenaline constricts the blood vessels increasing the blood pressure and adrenaline increases the heart rate and metabolism.
Reserpine works by significantly lowering catecholamines stores in adrenergic nerves and in the heart. This slows down the heart rate and helps open up capillaries and arterioles which in turn cause a reduction in blood pressure.
In a Cochrane review to investigate the dose related effect of reserpine on blood pressure, heart rate and withdrawals due to adverse events, the authors concluded that reserpine is effective in reducing systolic blood pressure approximately to the same degree as other first line anti-hypertensive drugs.
Dose: 1-2 gm of Sarpagandha powder once a day.
Side effects during treatment:
► Diarrhea, nausea and vomiting
► Loss of appetite
► Swelling of feet and lower legs
► Nightmares or early morning sleeplessness
Side effects after stopping treatment:
► Mental depression, nervousness or anxiety
► Impotence or decreased sexual interest
► Irregular or slow heart beat