Medindia

X

How to Wake Up Your Brain

by Kathy Jones on  September 23, 2010 at 6:30 PM Research News   - G J E 4
Staying awake and alert is important for accomplishing advanced tasks in daily life.
 How to Wake Up Your Brain
How to Wake Up Your Brain
Advertisement

It has been known so far that neuropeptide in the brain called "Orexin"controls sleep and awakening besides appetite. Here, the research group led by Dr. Akihiro Yamanaka, National Institute for Physiological Sciences (NIPS), found that orexin-releasing neurons have the self-excitation mechanism that activate each other among them, and maintain awaking. From this result, the application to doze prevention or insomnia treatment can be expected. It is reported in the Journal of Neuroscience of the issue on September 22, 2010(the United States EST).

Advertisement
The research group focused on the orexin-releasing neurons in cerebral hypothalamus. They found that the orexin-releasing neurons not only release orexins, but also receive the stimulation of them via the orexin receptor (mainly orexin receptor type 2) and activate each other among them. This mechanism enables the orexin-releasing neurons to keep high level activity, and to maintain awaking. There was the established theory that"the orexin does not act on to the orexin neuron" from the original research result of its discovery, but this discovery overturns it.

By this study, Dr. Yamanaka clarified the nerve mechanism which maintains awakening or raises awakening level. It can be considered that maintaining the orexin neuron activity highly by this mechanism is one of the insomnia mechanisms. He believes that this study results can be applied to the doze prevention and the treatment of the insomnia in the future.



Source: Eurekalert
Advertisement

Post your Comments

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.
User Avatar
* Your comment can be maximum of 2500 characters
Notify me when reply is posted I agree to the terms and conditions

You May Also Like

Advertisement
View All