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Side effect(s) of Mepolizumab


Review the side-effects of Mepolizumab as documented in medical literature. The term "side effects" refers to unintended effects that can occur as a result of taking the medication. In majority of the instances these side-effects are mild and easily tolerable, however sometimes they can be more severe and can be detrimental.

If the side effects are not tolerable adjusting the dosage or switching to a different medication can help to manage or overcome side effects. If you have any doubts or questions, we recommend seeking advice from your doctor or pharmacist.

  Gastrointestinal:
Pain in the stomach

  Central Nervous System:
Dizziness, headache

  Respiratory:
Influenza (a highly communicable viral disease caused by influenza virus which spreads through the air from coughing or sneezing)

  Skin:
Itchy skin, eczema, and injection site reaction with swelling, pain, redness and burning feeling at the injection site

  Musculoskeletal:
Muscle pain, backpain and severe weakness

  Allergic reactions:
Severe allergic reaction like angioedema (swelling under the skin), low blood pressure and bronchospasm may occur

  Herpes zoster infection:
Shingles could appear in some cases

Other Precautions :

• Patients should take medical advice if the asthma is not controlled during the drug treatment.
• The reconstituted solution must be checked visually for any particles or clarity.

Drug Name : Mepolizumab

Mepolizumab generic Mepolizumab is a monoclonal antibody used as an add-on maintenance treatment for treating patients with severe eosinophilic asthma. Eosinophilic asthma is a type of asthma where the number of white blood cells called eosinophils is high in the respiratory tract. The asthma can be severe and sometimes non-responsive to steroids. Mepolizumab is an interleukin-5 antagonist. It blocks the binding of interleukin-5 (a molecule produced by immune cells) to the eosinophils and thereby reduces the production, maturation, and circulation of the eosinophils. It is prescribed only for adults and children 12 years older. It stops the growth of cancer cells by blocking Tyrosine kinases.


Trade Names for Mepolizumab

International :


Nucala 100mg/vial
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