Why it is prescribed :
This combination medication contains angiotensin-converting enzyme (ACE) inhibitor and calcium channel blocker, prescribed for high blood pressure. It works by relaxing blood vessels.
When it is not to be taken (Contraindications):
Contraindicated in patients with low blood pressure, Second-or third-degree AV block, atrial flutter or atrial fibrillation and hypersensitivity.
Category D :
There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.
Dosage & When it is to be taken (Indications):
Usual dose: trandolapril 1- 4 mg/verapamil HCl ER 180-240 mg PO qD
How it should be taken :
It comes as a tablet to take by mouth, with food.
Warnings and Precautions :
Caution should be exercised in patients with history of heart disease, blood vessel problems, blood flow problems, bone marrow depression, kidney or liver problems, muscular dystrophy, neuromuscular disease, diabetes, fluid in the lungs, stroke, recent heart attack, kidney transplant, autoimmune disease, dehydration, increase or decrease in blood minerals, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness, light-headedness, or fainting, do not drive a car or operate machinery and sit up or stand slowly, while taking this medication.
Monitor liver function, kidney function, complete blood cell counts, and blood pressure
Regularly while taking this medication
Side Effects :
Slow heart rate, lung inflammation, chest pain, constipation, cough, diarrhea, dizziness, difficulty in breathing, fluid retention, fatigue, headache, increased liver enzymes, nausea, back pain, joint pain, upper respiratory tract infection.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store at 15°-25°C.