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Thymoglobulin

Latest prescription information about Thymoglobulin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Thymoglobulin
Pronunciation : THYE-moe-site GLOB-yoo-lin
Therapeutic Classification : Immunosuppressants
ICD Code : Y43.4
Trade Name(s): 
International- Tymoglobuline vial.
Why it is prescribed (Indications) : 
This medication is an immunosuppressant, prescribed for preventing organ rejection during kidney transplantation by reducing natural immunity. It is also used for aplastic anemia.  
When it is not to be taken (Contraindications): 
Contraindicated in people with viral illness, allergic to rabbit products and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adults— 1.5 milligrams for every kilogram (2.2 pounds) of your body weight injected into a vein every day for 7 to 14 days.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart failure, shortness of breath, or swelling in the legs, low blood counts, kidney or liver problems, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* It may affect platelet counts; avoid injury or bruising.
* Avoid contact with people who are prone to infection.
Side Effects : 
Most common- Chills, diarrhea, dizziness, fever, general body discomfort, headache, nausea, swelling of the hands and feet, urinary tract infection, weakness, easy bleeding or bruising, fast or irregular heartbeat, fever, infection, joint or muscle pain, sore throat, stomach pain, unusual fatigue.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Normally handled and stored by a healthcare provider.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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