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Clomiphene

Updated on : October - 2012
Latest prescription information about Clomiphene. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Clomiphene
Pronunciation : KLOE-mih-feen
Therapeutic Classification : Fertility Drug
Trade Name(s): 
India- Clofert Tab, Clomidac Tab Tab, Clomiriv Tab, Clomit Tab, Clopreg Tab, Clowin Tab, Fertik Tab, Fertilin Tab, Fertomid Tab, Ferton Tab, Fertotab Tab, Fertova Tab, Fetrop Tab, Folistim Tab, Fulfyn Tab, Mephy Tab, Omicite Tab, Ovagen Tab, Ovipreg Tab, Ovipro-Mf Forte Sg-Cap, Ovipro-Mf Sg-Cap, Ovitec Tab, Ovofar Tab, Ovuclom Tab, Pregmate Tab, Rejun Tab, Siphene Tab, Siphene-M Tab, Ubiphene Tab.
International- Clomid, Serophene.
Why it is prescribed (Indications) : 
This medication is an ovulatory stimulant, prescribed for infertility due to anovulation. It increases production of gonadotropins and causes the ovaries to release 1 or more eggs. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with liver or thyroid disease, brain tumor, pregnant or breast feeding women, or patients with allergy to the drug.

Pregnancy Category :

A B C D X
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Dosage & When it is to be taken : 
Oral: 50 mg/day for 5 days starting on the 5th day of menstrual cycle or at any time if there is absence of a menstrual period. It may be increased to 100 mg/day for the 2nd course as early as 30 days after previous therapy if needed. Total max: 6 treatment cycles.
How it should be taken : 
It comes as a tablet to take by mouth. It is usually taken once a day.
Warnings and Precautions : 
*It may cause, uterine fibroids, blurred vision, dizziness. Do not drive a car or operate machinery, especially in poor lighting, until you know how this medication affects you.
*Polycystic ovaries, evaluate presence of ovarian cyst before each cycle treatment.
Side Effects : 
Heart- Vasomotor flushes.
Central Nervous System- Headache, dizziness, lightheadedness.
Eye- Visual symptoms, blurring spots or flashes, double vision, photophobia.
Gastrointestinal- Abdominal pain/discomfort, distension, bloating, nausea, vomiting.
Genitourinary- Multiple pregnancies, abnormal ovarian enlargement, abnormal uterine bleeding; ovarian cyst formation, ovarian hyperstimulation syndrome , risk of ovarian tumor.
Liver- Liver function tests abnormalities.
Miscellaneous- Breast tenderness and hives.
Other Precautions : 
*Pregnancy with more than 1 fetus (eg, twins) is possible while taking this medication.Consult with your doctor about multiple pregnancy.
Storage Conditions : 
Oral: Store at 15-30°C.Store it in room temperature and in airtight container.
♦ Safety Labeling Changes Approved By FDA

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Member Comments ( 4 )
Hi, my doc prescribed me siphene-100 mg tablets for 5 days starting from 3rd day of my periods. but i missed 3rd & 4th day and started taking on 5th day only and just 3 tablets for 3 days -. please let me know if it is ok, & can we have sex the very next day after having tablet. please help ? my cycle is 24 days.
(Posted by Sheetu, India Date : 2/22/2013 )
Hi there i have the Rejun 50 tablet but I don't get my period every month the last period i had was in November 2012 and now it's January 24,2013 so what i would like to know is that can i take it without having my period or should i wait till i get my period.I married for 5 years now and i would love to give my Hubby a child and yes i have a son that's 12 years old now it's time to add more to the family, please help me someone need help .
(Posted by elouaze, United States Date : 1/24/2013 )
Hi the this is the 1st time I'll be using the rejun 50 I would like to can I take it without having a period or do I need to have a period to take this pill? And another reason is that I have a in irregular period my period does not come every month some times it come every six months or every year and I want to have a baby please help me let me no and if I can't take the pill because of no period please let me know what can I do to make my period come so that I could take this pill. Thanks you
(Posted by lolo1981, United States Date : 12/4/2012 )
madam one doubt at the same time contact both
(Posted by anukiran, India Date : 10/11/2012 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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