Why it is prescribed :
This medication is an anti-alcoholic agent. It is used to prevent the need for alcohol in people who have stopped drinking alcohol. It reduces the desire to consume alcohol.
When it is not to be taken (Contraindications):
Contraindicated to known hypersensitivity and history of severe kidney impairment.
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
The dose depends on patient’s body weight. The recommended dose is two 333 mg tablets (each dose should total to 666 mg) taken three times daily.
How it should be taken :
It comes as a tablet to take by mouth, three times per day, with or without meals.
Warnings and Precautions :
Caution should be exercised in patients with history of kidney disease, severe allergic reactions, patient under treatment with antidepressant, any planned surgery, elderly, children, during pregnancy and breastfeeding.
Patient may develop with suicidal thoughts, watch them carefully.
It may affect thinking ability or coordination, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.
Acamprosate will not treat or prevent alcohol withdrawal symptoms
Side Effects :
Body as a Whole
Accidental injury, weakness, headache, feeling shortness of breath, abdominal pain, back pain, infection and burning or numbness in the hands, feet, arms, or legs.
Central Nervous System
Anxiety, depression, dizziness, dry mouth, sleeplessness, tingling, drowsiness, decreased libido (sexual pleasure), memory loss, abnormal thinking, suicide attempt and tremor.
Palpitations, syncope (consciousness loss), vasodilatation, high/low blood pressure, fast heart rate, bleeding, chest pain, varicose vein, sudden heart attack, inflammation of blood vessels and postural hypotension (fall in the blood pressure when the person stands up suddenly).
Loss of appetite, diarrhea, flatulence, nausea, vomiting, blood vomiting, indigestion, constipation, increased appetite, inflammation of stomach, difficulty in swallowing, eructation, gastrointestinal bleeding, inflammation of pancreas and rectal bleeding.
Decrease in thyroid hormone.
Anemia, easy bruising, eosinophilia, increase in lymphocytes and decrease in platelets.
Peripheral edema, weight gain, weight loss, hyperglycemia, increase in liver enzyme, gout, thirst, vitamin deficiency and excess bilirubin in blood.
Itching, sweating, rash, pimples, hair loss, hive and dry skin.
Eye and ENT
Abnormal vision, taste perversion, ringing in the ear, poor vision or vision abnormalities and photophobia (sensitive to light).
Impotence, irregular periods, urinating less than usual or not at all, urinary tract infection, abnormal sexual function, urinary incontinence and vaginal inflammation.
Fever, sleep problems, intentional overdose, malaise (discomfortness), allergic reaction, abscess, neck pain, hernia (swelling or projection of an organ), intentional injury, flu syndrome, chest pain and chills.
Other Precautions :
Avoid excess or less dosage.
Storage Conditions :
Oral: Store it at room temperature (15-30°C), and in an airtight container.
Last Updated : August 2013