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Acamprosate - Indications, Dosage, Side Effects and Precautions

Last Updated on Nov 19, 2010
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Information about Acamprosate

Generic Name : Acamprosate
Pronunciation : a kam' pro sate
Latest prescription information about Acamprosate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, warnings and its storage instructions . Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y57.3 | Therapeutic Classification : Anti-alcoholic Agent
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Trade Names/Brand Names of Acamprosate

India : 

International : 

Campral
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Why is Acamprosate Prescribed? (Indications)

Acamprosate is used to treat alcohol dependence along with other rehabilitation therapy such as counseling and social support in people who have the intention of avoiding alcohol consumption.

Acamprosate reduces the desire to consume alcohol. 
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When should Acamprosate not be taken? (Contraindications)

Contraindicated to known hypersensitivity and history of severe kidney impairment.

What is the dosage of Acamprosate?

The dose depends on patient’s body weight. The recommended dose is two 333 mg tablets (each dose should total to 666 mg) taken three times daily.

How should Acamprosate be taken?

It comes as a tablet to take by mouth, three times per day, with or without meals.

What are the warnings and precautions for Acamprosate?

• Caution should be exercised in patients with history of kidney disease, severe allergic reactions, patient under treatment with antidepressant, any planned surgery, elderly, children, during pregnancy and breastfeeding.

• Patient may develop with suicidal thoughts, watch them carefully.

• It may affect thinking ability or coordination, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

• Acamprosate will not treat or prevent alcohol withdrawal symptoms

What are the side effects of Acamprosate?

  Body as a Whole: Accidental injury, weakness, headache, feeling shortness of breath, abdominal pain, back pain, infection and burning or numbness in the hands, feet, arms, or legs.
  Central Nervous System: Anxiety, depression, dizziness, dry mouth, sleeplessness, tingling, drowsiness, decreased libido (sexual pleasure), memory loss, abnormal thinking, suicide attempt and tremor.
  Heart: Palpitations, syncope (consciousness loss), vasodilatation, high/low blood pressure, fast heart rate, bleeding, chest pain, varicose vein, sudden heart attack, inflammation of blood vessels and postural hypotension (fall in the blood pressure when the person stands up suddenly).
  Gastrointestinal: Loss of appetite, diarrhea, flatulence, nausea, vomiting, blood vomiting, indigestion, constipation, increased appetite, inflammation of stomach, difficulty in swallowing, eructation, gastrointestinal bleeding, inflammation of pancreas and rectal bleeding.
  Endocrine System: Decrease in thyroid hormone.
  Blood : Anemia, easy bruising, eosinophilia, increase in lymphocytes and decrease in platelets.
  Metabolic : Peripheral edema, weight gain, weight loss, hyperglycemia, increase in liver enzyme, gout, thirst, vitamin deficiency and excess bilirubin in blood.
  Liver: Liver inflammation.
  Skin: Itching, sweating, rash, pimples, hair loss, hive and dry skin.
  Eye and ENT: Abnormal vision, taste perversion, ringing in the ear, poor vision or vision abnormalities and photophobia (sensitive to light).
  Genitourinary: Impotence, irregular periods, urinating less than usual or not at all, urinary tract infection, abnormal sexual function, urinary incontinence and vaginal inflammation.
  Miscellaneous: Fever, sleep problems, intentional overdose, malaise (discomfortness), allergic reaction, abscess, neck pain, hernia (swelling or projection of an organ), intentional injury, flu syndrome, chest pain and chills.

What are the other precautions for Acamprosate?

Avoid excess or less dosage.

What are the storage conditions for Acamprosate?

Oral: Store it at room temperature (15-30°C), and in an airtight container.
Last Updated : Jul 2018



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