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Ongoing research in the field of Cardiac Markers
Owing to the vitality of cardiac markers active researches are being carried out. Some of the targets include:
- Standardization of methods for measuring current markers, troponin I in particular.
- The assessment of rapid bedside tests
- To investigate the relationship between cardiac markers and emerging immunological coagulation parameters.
References:
- Cecil Medicine, 23rd Ed. Harrison's PRINCIPLES OF INTERNAL MEDICINE, 17TH Edition
- Cardiovasc Pathol. 2007 Nov-Dec;16(6):329-35. Epub 2007 Jun 20.
- INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH Volume 29, Number 2, 56-63, DOI: 10.1007/s005990050064
The ischemic biomarker Heart-type Fatty Acid Binding Protein [H-FABP] can substantially improve the detection of high risk patients when Troponin-negative, even when a high sensitivity assay is used, a new publication has shown. In the June edition of JACC, Professor Alistair Hall and colleagues from the University of Leeds, UK, prospectively studied a cohort of 1080 consecutive patients admitted to hospital with suspected ACS and compared the H-FABP assay (Randox Laboratories) with the high sensitivity Ultra-TnI assay (Siemens Healthcare Diagnostics).