Men who are younger or have a lower body mass index (BMI) are more prone to experience hot flashes during a common treatment for patients with advanced stage prostate cancer, finds a new research.
More than 25% of prostate cancer patients report that hot flashes are the most distressing side effect of androgen deprivation therapy (ADT).
Prostate Cancer Screening
PSA (Prostate Specific Antigen) test and Digital Rectal Examination are two tests that allow detection of prostate cancer at early stages.
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"This study is a concrete step towards identifying which patients are more likely to experience these distressing symptoms," said Mayer Fishman from the Moffitt Cancer Center in Florida, US.
The researchers also reported that the presence of certain genes involved in processes such as immune function, nerve impulse transmission, blood vessel constriction and circadian rhythms were associated with an increased number of hot flashes.
![Prostate Cancer: Treatment Options]( "Prostate Cancer: Treatment Options")
Treatment options of prostate cancer includes waiting, surgery, radiation, hormone therapy, chemotherapy, cryosurgery or biologic therapy.
They compared 60 prostate cancer patients on ADT to 83 prostate cancer patients who did not have ADT and 86 men without cancer.
They discovered that patients on ADT experienced significantly more hot flashes at six months and 12 months after therapy initiation than the other two control groups combined.
The severity of the hot flashes also increased over time in the group of men receiving ADT.
The patients reported that the hot flashes interfered with their daily lives by affecting leisure activities, sleep and general quality of life.
The researchers analyzed patient characteristics and their DNA to determine which factors were associated with an increase of hot flashes.
The study appeared in The Journal of Urology.
Source: IANS
Prostate Cancer: Treatment Options
Treatment options of prostate cancer includes waiting, surgery, radiation, hormone therapy, chemotherapy, cryosurgery or biologic therapy.
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They compared 60 prostate cancer patients on ADT to 83 prostate cancer patients who did not have ADT and 86 men without cancer.
They discovered that patients on ADT experienced significantly more hot flashes at six months and 12 months after therapy initiation than the other two control groups combined.
The severity of the hot flashes also increased over time in the group of men receiving ADT.
The patients reported that the hot flashes interfered with their daily lives by affecting leisure activities, sleep and general quality of life.
The researchers analyzed patient characteristics and their DNA to determine which factors were associated with an increase of hot flashes.
The study appeared in The Journal of Urology.
Source: IANS
![Prostate Specific Antigen [PSA]](https://www.medindia.net/images/patientinfo/300x250/prostate-specific-antigen.jpg "Prostate Specific Antigen [PSA]")
Prostate Specific Antigen [PSA]
PSA blood test is specific to prostate gland but not necessarily a cancer specific test but is commonly used to diagnose prostate cancer.
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