About two-thirds of American adults are overweight or obese, and the economic and health burdens of the obesity epidemic are substantial. Achieving and maintaining weight loss has proven to be difficult. Most people lose, gain and maintain their weight inconsistently, and those who lose the most weight are most likely to keep it off and keep losing, suggests a new research.
Study lead author Joanna Huang, senior manager of health economics and outcomes research at Novo Nordisk Inc. in Plainsboro, New Jersey said, "Many patients regain weight after their initial loss; and even after a period of weight loss, most people become 'cyclers' who regain weight or experience inconsistent losses and gains."
To analyze trends in weight change, Huang and her colleagues reviewed the electronic medical records of 177,743 obese patients who had no medical conditions associated with unintentional weight loss and who had been having annual body mass index (BMI) measurements for five years or longer.
Patients who lost more weight early on were more likely to continue to lose weight over time. Among patients with modest weight loss, 23.1% maintained their weight and 2% continued to lose weight over the two-year monitoring period; in those with moderate weight loss, 14.1% maintained their weight loss and 4.1% continued to lose weight; and in those with high weight loss, 19.4% maintained their weight and 11.1% continued to lose weight.
But over the two years, fewer patients maintained their weight. In the modest, moderate, and high weight-loss groups, 40%, 35.9%, and 18.6% of patients, respectively, regained over half of their lost weight during the maintenance period.
And most patients in each group experienced weight cycling or weight regain. The high weight-loss group had the lowest proportion of cyclers with 58.3%, while 71.5% of the modest weight loss group and 74.1% of the moderate weight loss group were cyclers.
"These important challenges require further attention. We hope these results highlight the importance of chronic, consistent and conscientious weight loss and management," Huang said. "Identifying patterns of weight change is critical for tailoring weight management strategies to the needs of targeted patient groups."