About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

US Authorities Loosen Restrictions on Experimental Ebola Drug for Testing on Infected Patients in Africa

by Kathy Jones on August 8, 2014 at 11:35 PM
Font : A-A+

 US Authorities Loosen Restrictions on Experimental Ebola Drug for Testing on Infected Patients in Africa

Even as controversy rages over disparity in Ebola treatment available for Americans and Africans, a Canadian company revealed that American health regulators have loosened restrictions on another experimental drug for treating the infection and it may be tested on infected patients in West Africa.

The Canada-based company, Tekmira, said the US Food and Drug Administration changed the classification of its drug TKM-Ebola from full clinical hold to partial hold.

Advertisement

"This action enables the potential use of TKM-Ebola in individuals infected with Ebola virus," said a company statement.

Tests on monkeys have shown the drug provided 100 percent protection from an otherwise lethal dose of Ebola, the company said.

West Africa is experiencing the largest outbreak of Ebola in history. The virus has killed 932 people of more than 1,700 infected, and the disease continues to spread.
Advertisement

"This current outbreak underscores the critical need for effective therapeutic agents to treat the Ebola virus," said Mark Murray, CEO and president of Tekmira Pharmaceuticals.

"We recognize the heightened urgency of this situation, and are carefully evaluating options for use of our investigational drug within accepted clinical and regulatory protocols."

TKM-Ebola is being developed under a $140 million contract with the US Department of Defense's Medical Countermeasure Systems BioDefense Therapeutics Joint Product Management Office.

The drug, described as an anti-Ebola virus RNAi therapeutic, is designed to be given in multiple doses, which is not always practical in a mass outbreak.

However, there are no drugs on the market to treat Ebola and no vaccines against it.

The rapidly growing outbreak in West Africa has sped up the process of getting experimental therapies to market, though experts say it may be months before production can be scaled up and the drugs delivered to those in need.

The two American missionaries who were evacuated from Liberia in recent days were given a different experimental serum known as ZMapp.

Both Kent Brantly and Nancy Writebol are improving, but health authorities say it is too early to tell if the drug had anything to do with that.

Source: AFP
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
How to Battle Boredom during COVID
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Drug Toxicity Signature Drug Toxicity Congo Fever Ebola Virus Disease 

Recommended Reading
Ebola Virus Disease
Ebola is caused by a virus via direct contact with body fluids or infected blood. Scientists have .....
Ebola Spread to US ‘Inevitable’ Though Outbreak Will be on Small Scale: CDC Chief
While two Americans have been infected with the Ebola virus, both of them have contracted the virus ...
Britain Raises Ebola Outbreak Aid by Further $5 Million
The British government has announced that it will be extending its aid to healthcare systems in ......
Public Sector Doctors in Nigeria Decide to Suspend Strike as Ebola Outbreak Hits Their Shores
Nigerian public sector doctors have announced that they will be suspending a five-week long strike ....
Congo Fever
Crimean-Congo Hemorrhagic fever (CCHF) is a viral disease that affects people who are bitten by infe...
Drug Toxicity
Drug toxicity is an adverse reaction of the body towards a drug that results as a side effect of a d...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use