
In predisposed children, early exposure to complex foreign proteins, such as cow's milk proteins, increases the risk of type 1 diabetes, indicate previous studies.
"Therefore, In 2002, we embarked on a large-scale study on more than 2100 infants with a family member affected by type 1 diabetes and with genetic disease susceptibility to find an answer to the question whether delaying the exposure to complex foreign proteins will decrease the risk of diabetes", tells Professor Mikael Knip from the University of Helsinki, the leader of the trigr.epi.usf.edu.
After breastfeeding the babies were either weaned to a special formula, where the cow's milk proteins were split into small peptides, or to a conventional infant formula with the regular cow's milk proteins. The first study endpoint was positivity for at least two diabetes-associated autoantibodies by the age of six years.
"The current results do not exclude the possibility that the early dietary modification may affect the latter phase, and therefore it is extremely important to continue to follow the study participants into the final endpoint, which is the age of ten years. That endpoint will be reached in 2017", Professor Knip states.
Source: Eurekalert
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