Scientists have demonstrated that that mesoporous silica nanoparticles (MSNs), tiny particles with thousands of pores, can store and deliver chemotherapeutic drugs in vivo and effectively suppress tumors in mice.
Researchers at UCLA's California NanoSystems Institute and Jonsson Comprehensive Cancer Center also showed that MSNs accumulate almost exclusively in tumors after administration and that the nanoparticles are excreted from the body after they have delivered their chemotherapeutic drugs.
Scientists Say Nanoparticles in Sunscreens Could be Toxic If Accidentally Eaten
Scientists have said that nanoparticles in sunscreens could be toxic if accidentally eaten.
Advertisement
In the study, researchers found that MSNs circulate in the bloodstream for extended periods of time and accumulate predominantly in tumors.
The tumor accumulation could be further improved by attaching a targeting moiety to MSNs, the researchers said.
The treatment of mice with camptothecin-loaded MSNs led to shrinkage and regression of xenograft tumors.
By the end of the treatment, the mice were essentially tumor free, and acute and long-term toxicity of MSNs to the mice was negligible.
The study has been published July 8 in the journal Small.
Source: ANI
The treatment of mice with camptothecin-loaded MSNs led to shrinkage and regression of xenograft tumors.
By the end of the treatment, the mice were essentially tumor free, and acute and long-term toxicity of MSNs to the mice was negligible.
The study has been published July 8 in the journal Small.
Source: ANI
Accidental Consumption of Sunscreen Nanoparticles Could be Toxic
A new study has said that nanoparticles of zinc oxide present in sunscreens could prove toxic if consumed accidentally.
Advertisement
 Tumors can be Killed by Gold NanoparticlesScientists from Washington University in St.Louis are in the process of developing a 'golden' bullet for cancer, which will use gold nanoparticles to kill the tumours. | Advertisement
|
'Smart' Nanoparticles Can Target Specific Cancer Cells
Scientists in the U.S. have created synthesized nanoparticles that can identify, target and kill specific cancer cells while leaving healthy cells alone.
Advertisement
Latest Cancer News
The mechanism by which the kinases cause inflammation has been discovered by scientists.
Pancreatic cancer cases are on the rise. The biomarker approach could reduce the chance of developing pancreatic cancer.
New combination of medications trametinib and entinostat were found to decrease lung cancer in mice.
Combination treatment with TALZENNA and XTANDI was found to benefit prostate cancer patients, revealed study.
In leukemia patients, reduced amounts of dietary vitamin A is associated with a higher risk and severity of pancreatitis.