About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Synthetic DNA Motor can Help in Early Detection of Cancer

by Bidita Debnath on March 6, 2017 at 11:50 PM
Font : A-A+

 Synthetic DNA Motor can Help in Early Detection of Cancer

Scientists have shown that synthetic DNA motors can work in living cells and help early detection of deadly diseases such as cancer and also make drug delivery more precise.

"This is really big because of the diverse potential applications," said one of the researchers Chris Le, Professor at University of Alberta in Canada.

Advertisement


"One outcome of this will be to provide better and earlier disease detection. Another is the controllable release of targeted drug molecules within patients, resulting in fewer side effects," Le said.

The process -- previously only successful in test tubes -- was described in a study published in the journal Nature Communications.

The team created the nanomachine from compartments made up of DNA enzyme molecules and substrates.
Advertisement

"This nanomachine has the required fuels, DNA tracks, and a molecular switch," said Hongquan Zhang, Assistant Professor at University of Alberta, Canada.

For the study, it was 'tuned' to detect a specific microRNA sequence found in breast cancer cells.

When it came into contact with the targetted molecules, the DNA motor was turned on and produced fluorescence as part of a reaction.

The researchers were able to monitor the fluorescence, detecting which cells were cancerous.

"We want to be able to detect cancer or disease markers in very minute amounts before the disease gets out of hand. That way physicians can attack it very early," Le said.

"The trace amount of the target molecules that may be missed by other techniques can now be detected with this one," Le noted.

In addition to the potential for improved disease diagnosis, the researchers said DNA motors could also be used for precision drug delivery in patients.

Conventional targetted drug therapy delivers medicine to a selectively targeted site of action, yet it still affects a large number of molecules that are not diseased.

With the DNA motor, a drug payload can be delivered and then released only when triggered by disease specific molecules, the researchers said.

Source: IANS
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
What's New on Medindia
World AIDS Day 2022 - Equalize!
Test Your Knowledge on Sugar Intake and Oral Health
Test  Your Knowledge on Heart
View all
Recommended Reading
News Archive
Date
Category
Advertisement
News Category

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
DNA Finger Printing Cancer and Homeopathy Cancer Facts Genetic Testing of Diseases Cancer Tattoos A Body Art Epigenetics Common Lifestyle Habits that Cause Diseases Health Benefits of Dandelion Plant Oxidative Stress / Free Radicals Cell Injury 

Most Popular on Medindia

Nutam (400mg) (Piracetam) Selfie Addiction Calculator Blood Donation - Recipients Loram (2 mg) (Lorazepam) Blood - Sugar Chart Calculate Ideal Weight for Infants Find a Hospital Sinopril (2mg) (Lacidipine) The Essence of Yoga Sanatogen
This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
×

Synthetic DNA Motor can Help in Early Detection of Cancer Personalised Printable Document (PDF)

Please complete this form and we'll send you a personalised information that is requested

You may use this for your own reference or forward it to your friends.

Please use the information prudently. If you are not a medical doctor please remember to consult your healthcare provider as this information is not a substitute for professional advice.

Name *

Email Address *

Country *

Areas of Interests