About My Health Careers Internship MedBlogs Contact us

Study Shows Strong Association Between Elevated Insulin Levels And Increased Risk For Breast Cancer

by Aruna on July 13, 2009 at 11:38 AM
Font : A-A+

Study Shows Strong Association Between Elevated Insulin Levels And Increased Risk For Breast Cancer

A new study at Albert Einstein College of Medicine of Yeshiva University has shown that elevated insulin levels in the blood could raise the risk of breast cancer in postmenopausal women.

Increased breast cancer risk in postmenopausal women has previously been linked to obesity and diabetes. Both conditions involve insulin resistance, which causes increases in circulating levels of insulin.


Since insulin is known to promote cell division and enhance breast tumor growth in animal models, the Einstein scientists reasoned that relatively high insulin levels might contribute to breast cancer risk in women.

"Up to now, only a few studies have directly investigated whether insulin levels are associated with breast cancer risk, and those studies have yielded conflicting results," says Geoffrey Kabat, Ph.D., senior epidemiologist in the department of epidemiology and population health at Einstein and the lead author of the paper.

"Those other studies were based on just a single baseline measurement of insulin, while our study involved analyzing repeated measurements of insulin taken over several years, which provides a more accurate picture of the possible association between insulin levels and breast cancer risk," Kabat added.

In the new study, Dr. Kabat and his colleagues analyzed data on 5,450 women enrolled in the Women's Health Initiative, a large multicenter study investigating the influence of a number of factors on women's health. Most of the women had participated in the clinical trial portion of the study and provided fasting blood samples at the start of the study (i.e., at baseline) and then at years one, three and six.

The remaining women, who were enrolled in a separate "observational" component of the study, provided fasting blood samples at baseline and at year three of the study. Among all these women, 190 cases of breast cancer were identified over eight years of follow-up.

The results showed a strong association between elevated insulin levels and increased risk for breast cancer.

"This finding is potentially important because it indicates that, in postmenopausal women, insulin may be a risk factor for breast cancer that is independent of obesity," Dr. Kabat said.

Their findings are published in the online version of the International Journal of Cancer.

Source: ANI

News A-Z
News Category
What's New on Medindia
First Dose of COVID-19 Vaccines May Improve Mental Health
Printed Temperature Sensors help with Continuous Temperature Monitoring
Health Benefits of Giloy
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Women and Cancer Pagets disease of the breast Mastitis Diabetes - Essentials Cancer and Homeopathy Breast Cancer Facts Cancer Facts Gestational diabetes Cancer Tattoos A Body Art 

Recommended Reading
Scientists Identify Promising Drug Target for Aggressive Form of Breast Cancer
A potential target for the treatment of the most aggressive forms of breast cancer has been ......
Breast Cancer Hormone Receptor Status Linked to Risk of a Second Primary Tumor
A study published online July 9 in the Journal of the National Cancer Institute says that wom...
Many Women Treated Needlessly for Breast Cancer: Study
A third of women diagnosed with breast cancer in public screening programmes are treated needlessly ...
Diabetes - Essentials
Diabetes is a metabolic disease caused by insulin deficiency that leads to high blood sugar levels a...
Gestational diabetes
The condition is not caused by a lack of insulin, but by the action of hormones produced during preg...
Mastitis is a common cause of tenderness, swelling and pain in breast, owing to inflammation in the ...
Pagets disease of the breast
A detailed description of the Paget's disease of the breast, characteristic signs and symptoms, dete...
Tattoos A Body Art
Tattoos are a rage among college students who sport it for the ‘cool dude’ or ‘cool babe’ look...
Women and Cancer
Cancer is one of the frequently talked about and most feared disease that falls under the genre of l...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use