Medindia
Advertisement

Study Provides Insights on Enzyme That Helps Direct Immune Response in Acute Kidney Injury

by Dr. Trupti Shirole on February 14, 2015 at 3:03 PM
Font : A-A+

 Study Provides Insights on Enzyme That Helps Direct Immune Response in Acute Kidney Injury

An enzyme called heme oxygenase-1 (HO-1) known to be important in the body's response to kidney injury exerts its protective effects, in part, by affecting the immune system, revealed to a study by researchers at University of Alabama, Birmingham. These findings could lead to new treatments for patients with acute kidney injury (AKI).

AKI is an abrupt decline in kidney function that often arises after major surgeries or severe infections, and heme oxygenase-1 (HO-1) is known to be important in the body's protective response to AKI. Lead researcher Dr. Anupam Agarwal said, "This pre-clinical study more completely defines the cellular compartments through which HO-1 exerts its protective effects in AKI, thus paving the way for the development of targeted novel therapeutic strategies aimed at preventing the significant morbidity and mortality caused by AKI in patients. More importantly, our studies discovered that the absence of HO-1 in myeloid cells had a dramatic effect on recovery after AKI, suggesting that HO-1 could be an important target in preventing the transition of AKI to chronic kidney disease."

Advertisement

The study is published in the 'Journal of the American Society of Nephrology' (JASN).

Source: Medindia
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Sedentary Behavior Precipitates Night-Time Hot Flashes
Gonorrhea
World Alzheimer's Day 2021 - 'Know Dementia, Know Alzheimer's
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Athletes Foot Urinary Stones In Children Vesico-Ureteric Reflux Causing UTI in Children Hydronephrosis / Antenatal Counseling Urology Paediatric Emergencies Cysts and Tumours Kidney Disease Kidney Kidney Health Stones in Urinary Tract 

Recommended Reading
World Kidney Day 2013 - Kidneys for Life: Stop Kidney Attack
The eighth World Kidney Day focuses on Acute Kidney Injury, a common life threatening condition....
Acute Kidney Injury Treated With a Mood Stabilizing Drug
A new study found how acute kidney injury may now be treated with a mood stabilizing drug...
Higher Intensity Renal Replacement Therapy Not Beneficial for Acute Kidney Injury Patients
Patients with acute kidney injury in an intensive care unit requiring renal replacement therapy do ....
Chronic Kidney Disease and Acute Kidney Injury Each a Risk of the Other
Chronic kidney disease (CKD) and Acute kidney injury (AKI) are closely intertwined, with each ......
Athletes Foot
Athlete’s foot (tinea pedis/ringworm of the foot) is a fungal infection of the feet....
Cysts and Tumours
Ultrasound scan reveals multiple cysts and there is no function on that kidney when tested on DMSA s...
Hydronephrosis / Antenatal Counseling
Currently most pregnant women undergo one or two ultrasound scans during their pregnancy....
Stones in Urinary Tract
Ask people who have suffered from urinary stones and they will tell you how excruciating the pain ca...
Urinary Stones In Children
There is a wide misconception that only adults develop stones. On the contrary kidney stones are ver...
Urology Paediatric Emergencies
The testis can go for a twist inside the sac it is held. This results in loss of blood supply. If le...
Vesico-Ureteric Reflux Causing UTI in Children
Bacterial infection of urinary bladder can cause pain and burning sensation while passing urine. Abn...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use