Elderly are more prone to falls increasing their risk of fractures. But sportspersons are at risk of stress fractures and this could be influenced by genes, revealed a new study.
Researchers have identified how certain genes can contribute towards a person's susceptibility to stress fracture injuries, a fatigue-induced fracture of the bone caused by repeated pressure over time.
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‘Two distinct variations within the purinergic receptor genes are associated with stress fracture injuries.
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Unlike normal fractures, stress fractures are the result of accumulated trauma from repeated mechanical usage, such as running or jumping. As such, stress fractures are common injuries for athletes and military personnel.
In this study, the researchers aimed to identify the contribution a specific gene had to stress fracture injuries in two groups of volunteers made up of military recruits and elite athletes.
![Stress Fracture Risk Now Down, Thanks to New Programmes]( "Stress Fracture Risk Now Down, Thanks to New Programmes")
Researchers claim that programs aimed at improving movement patterns may help reduce the risk of stress fractures in athletes and military personnel
The researchers evaluated the contribution the specific gene, P2X7R, had on the volunteers. The study was published in the journal Purinergic Signaling.
"The study found that two specific variations within the gene were associated with stress fracture injuries in healthy, exercising individuals," said one of the researchers Jim Gallagher from the University of Liverpool in England.
"The findings are the first to demonstrate an independent association between stress fracture injury and specific variations in purinergic receptor genes," Mr Gallagher noted.
The effect of heavy repeated mechanical usage causes an amalgamation of micro-damage in bone. The body responds to this through a process known as 'bone remodeling', in which the damaged bone is removed and healthy bone is deposited. Bone remodeling occurs continuously through our lives and helps us keep our bones healthy.
"This work builds on pioneering basic laboratory research over several years in which we first showed that purinergic receptors are expressed in bone cells and that they regulate the response of bone to mechanical loading," Mr Gallagher pointed out.
Source: IANS
Stress Fracture Risk Now Down, Thanks to New Programmes
Researchers claim that programs aimed at improving movement patterns may help reduce the risk of stress fractures in athletes and military personnel
Advertisement
The researchers evaluated the contribution the specific gene, P2X7R, had on the volunteers. The study was published in the journal Purinergic Signaling.
"The study found that two specific variations within the gene were associated with stress fracture injuries in healthy, exercising individuals," said one of the researchers Jim Gallagher from the University of Liverpool in England.
"The findings are the first to demonstrate an independent association between stress fracture injury and specific variations in purinergic receptor genes," Mr Gallagher noted.
The effect of heavy repeated mechanical usage causes an amalgamation of micro-damage in bone. The body responds to this through a process known as 'bone remodeling', in which the damaged bone is removed and healthy bone is deposited. Bone remodeling occurs continuously through our lives and helps us keep our bones healthy.
"This work builds on pioneering basic laboratory research over several years in which we first showed that purinergic receptors are expressed in bone cells and that they regulate the response of bone to mechanical loading," Mr Gallagher pointed out.
Source: IANS
Olympic Runners Aided In Recovery from Injuries By 'Anti-Gravity Treadmill'
Due to the repetitive impact of their feet hitting the ground, Olympic track stars and recreational runners alike can develop stress fractures in bones or soft tissue injuries in joints.
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