The new research explores aerobic exercise as a key element in preventing Alzheimer’s disease.
Tau, amyloid, iron, oligodendrocytes ferroptosis, and inflammaging in the hippocampal formation of aged rats submitted to an aerobic exercise program
Go to source) Published in the journal Brain Research, the study highlights how physical activity not only protects healthy brain cells but also restores balance in the aging brain.
Alzheimers Disease
Alzheimer''s disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others.
Alzheimer''s disease is a progressive neurodegenerative disease affecting memory and thinking and making the person increasingly dependent on others.
‘Move your body, protect your brain! Research points to the potential of regular #aerobicexercise in combating #Alzheimer's. #brainhealth’
Exercise and Alzheimer's: A Deep Dive into Hippocampal Pathology
The research focused on the hippocampus, the brain region responsible for memory and learning, and measured the impact of aerobic exercise on key Alzheimer's markers: amyloid plaques, tau tangles, and iron accumulation in myelin-producing cells known as oligodendrocytes. These markers are central to Alzheimer’s pathology.Findings revealed that rodents who completed a structured aerobic exercise programme experienced:
Significant reductions in tau tangles (around 63% with exercise), amyloid plaques (about 76% in the exercise group), and iron accumulation (reduced by about 58% in the brains of exercising rodents).
Benefits of Aerobic Exercises
Aerobics is a physical exercise that includes activities like dance, cycling, running, stretching and many more. Aerobic exercise can benefit your health in many ways.
Aerobics is a physical exercise that includes activities like dance, cycling, running, stretching and many more. Aerobic exercise can benefit your health in many ways.
Reduced brain inflammation in the exercise group (between 55% and 68% depending on the inflammatory biomarker considered), and cell death.
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Caring for Alzheimers disease patients
Alzheimer's disease is a complex brain disorder that triggers the most common form of dementia. The slide show will show how patients need support and care as dementia progresses.
Alzheimer's disease is a complex brain disorder that triggers the most common form of dementia. The slide show will show how patients need support and care as dementia progresses.
Dr. Augusto Coppi, Senior Lecturer in Veterinary Anatomy at the University of Bristol and one of the study’s senior authors, explained: “Alzheimer’s is a progressive neurodegenerative disorder with no known cure, impacting millions worldwide. While physical exercise is known to reduce cognitive decline, the cellular mechanisms behind its neuroprotective effects have remained elusive—until now.”
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Test your Knowledge on Exercise Addiction
Exercise addiction, or exercise dependence, is a compulsive habit of engaging in an extreme physical activity performed beyond the required level of fitness. Exercise addicts may start physical activity for weight control and falsely believe that ...
Exercise addiction, or exercise dependence, is a compulsive habit of engaging in an extreme physical activity performed beyond the required level of fitness. Exercise addicts may start physical activity for weight control and falsely believe that ...
Reference:
- Tau, amyloid, iron, oligodendrocytes ferroptosis, and inflammaging in the hippocampal formation of aged rats submitted to an aerobic exercise program - (https://www.sciencedirect.com/science/article/abs/pii/S0006899324006747?via%3Dihub)
Source-Eurekalert
